Guanosine, 2′,3′,5′-tribenzoate is a chemical compound derived from guanosine, a nucleoside that consists of the nitrogenous base guanine attached to a ribose sugar. The designation "2′,3′,5′-tribenzoate" indicates that three benzoate groups are esterified to the hydroxyl groups at the 2′, 3′, and 5′ positions of the ribose moiety. This modification enhances the lipophilicity of the molecule, potentially affecting its solubility and permeability across biological membranes. The compound is characterized by its ability to participate in biochemical processes, particularly in relation to nucleic acid metabolism and signaling pathways. Its CAS number, 66048-53-1, uniquely identifies this specific compound in chemical databases. Guanosine derivatives, including tribenzoates, are of interest in medicinal chemistry and biochemistry for their roles in cellular functions and potential therapeutic applications. The presence of multiple benzoate groups may also influence the compound's interaction with proteins and nucleic acids, making it a subject of study in drug design and molecular biology.

Guanosine, 2′,3′,5′-tribenzoate

66048-53-1: 2',3',5'-tris-O-(phenylcarbonyl)guanosine, Guanosine, 2′,3′,5′-tribenzoate

2'',3'',5''-Tri-O-benzoylguanosine

2',3',5'-Tri-O-benzoylguanosine is an anticancer nucleoside that inhibits the synthesis of DNA and RNA. It is a novel synthetic monophosphate nucleoside analog with antiviral and antitumor activities. 2',3',5'-Tri-O-benzoylguanosine has shown to be effective against human leukemia cells, lymphoma cells, prostate cancer cells, and melanoma cells in vitro. The drug also inhibits the growth of HIV virus in vitro.

CAS 66048-53-1: Guanosine, 2′,3′,5′-tribenzoate

2'',3'',5''-Tri-O-benzoylguanosine

Ref: 7W-GN8264

2',3',5'-Tri-O-benzoylguanosine

Ref: 3D-NT05368