CAS 6681-13-6: (4aS,16aS)-3,4,4a,5,16a,17,18,19-Octahydro-12,20,21,22,26-pentamethoxy-4,17-dimethyl-16H-1,24:6,9-dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline
Formula:C39H44N2O7
InChI:InChI=1S/C39H44N2O7/c1-40-16-14-25-21-32(43-4)34-22-28(25)29(40)18-23-8-11-26(12-9-23)47-33-20-24(10-13-31(33)42-3)19-30-35-27(15-17-41(30)2)36(44-5)38(45-6)39(46-7)37(35)48-34/h8-13,20-22,29-30H,14-19H2,1-7H3/t29-,30-/m0/s1
InChI key:InChIKey=FUZMQNZACIFDBL-KYJUHHDHSA-N
SMILES:O(C)C1=C2C3=C(C(OC)=C1OC)CCN(C)[C@]3(CC=4C=C(C(OC)=CC4)OC=5C=CC(C[C@]6(C7=CC(O2)=C(OC)C=C7CCN6C)[H])=CC5)[H]
Synonyms:- (+)-Hernandezine
- (4aS,16aS)-3,4,4a,5,16a,17,18,19-Octahydro-12,20,21,22,26-pentamethoxy-4,17-dimethyl-16H-1,24:6,9-dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline
- 16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, 3,4,4a,5,16a,17,18,19-octahydro-12,20,21,22,26-pentamethoxy-4,17-dimethyl-, (4aS,16aS)-
- 16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, berbaman deriv.
- Berbaman, 5,6,6',7,12-pentamethoxy-2,2'-dimethyl-, (1beta)-
- Berbaman, 5,6,6′,7,12-pentamethoxy-2,2′-dimethyl-, (1β)-
- Hernandesine
- Thalicsimine
- (1beta)-5,6,6',7,12-Pentamethoxy-2,2'-dimethylberbaman
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Found 6 products.
Hernandezine
CAS:Hernandezine is an activator of AMPK activator and a selective reversing agent for ABCB1-mediated MDR in cancer cells.Formula:C39H44N2O7Purity:99.53%Color and Shape:SolidMolecular weight:652.78Hernandezine
CAS:Hernandezine is a natural compound that belongs to the class of bisbenzylisoquinoline alkaloids. It is extracted from the bark of Quillaja saponaria, a chinese herb. Hernandezine has been shown to induce autophagy and inhibit lipid accumulation in hl-60 cells. This drug also has antitumor and antimetastatic effects on brain tumor cells, as well as anti-inflammatory properties. Hernandezine inhibits Ca2+ uptake in mitochondria, which can lead to cell death. Hernandezine has been shown to be a potential drug transporter for fat cells and may have immunosuppressive effects on autoimmune diseases such as diabetes or arthritis.Formula:C39H44N2O7Purity:Min. 95%Molecular weight:652.8 g/molHernandezine
CAS:Controlled ProductApplications Hernandezine is a novel anticancer AMPK activator identified as a major major active constituent of Thalictrum Ranunculaceae. References Song, Y. et al.: J. Pharm. Biomed. Anal., 141, 132 (2017);Formula:C39H44N2O7Color and Shape:NeatMolecular weight:652.776
