1H-benzimidazol-4-ol, with the CAS number 67021-83-4, is a heterocyclic organic compound characterized by its fused benzene and imidazole rings, featuring a hydroxyl group at the 4-position of the benzimidazole structure. This compound typically appears as a white to off-white solid and is soluble in polar solvents such as water and alcohols, owing to the presence of the hydroxyl group. It exhibits properties that make it of interest in various fields, including medicinal chemistry, where it may serve as a scaffold for the development of pharmaceuticals due to its potential biological activity. The compound can participate in hydrogen bonding due to the hydroxyl group, influencing its reactivity and interactions with other molecules. Additionally, 1H-benzimidazol-4-ol may exhibit fluorescence, making it useful in certain analytical applications. Its stability and reactivity can vary depending on the conditions, such as pH and temperature, which are important considerations in its practical applications.

1H-benzimidazol-4-ol

4-Hydroxybenzimidazole

1H-Benzimidazol-4-ol is a phenoxy compound that has neuroprotective effects. It is a metal chelator and also binds to hydroxybenzothiazole, which is a neuroprotective agent. 1H-Benzimidazol-4-ol has been shown to have neuroprotective effects in animal models of Alzheimer’s disease by minimizing the amount of beta amyloid protein and tau protein. This drug also has stereoselective properties, which may be due to its ability to maximize the spacing between the benzimidazole group and the piperidine ring.

CAS 67021-83-4: 1H-benzimidazol-4-ol

4-Hydroxybenzimidazole

Ref: 3B-H1547

1H-Benzimidazol-4-ol

Ref: 3D-FB173077

1H-Benzo[d]imidazol-4-ol

Ref: 10-F241143

1H-Benzo[d]imidazol-4-ol

Ref: IN-DA0064JY

1H-Benzoimidazol-4-ol

Ref: 54-OR943594