CymitQuimica logo

CAS 6754-13-8: Helenalin

Formula:C15H18O4
InChI:InChI=1S/C15H18O4/c1-7-6-10-12(8(2)14(18)19-10)13(17)15(3)9(7)4-5-11(15)16/h4-5,7,9-10,12-13,17H,2,6H2,1,3H3/t7-,9+,10-,12-,13+,15+/m1/s1
InChI key:InChIKey=ZVLOPMNVFLSSAA-XEPQRQSNSA-N
SMILES:C[C@@]12[C@]([C@H](C)C[C@@]3([C@]([C@@H]1O)(C(=C)C(=O)O3)[H])[H])(C=CC2=O)[H]
Synonyms:
  • (3aS)-3,3aalpha,4alpha,4a,7aalpha,8,9,9aalpha-Octahydro-4-hydroxy-4abeta,8 alpha-dimethyl-3-methyleneazuleno(6,5-b)-furan-2,5-dione
  • (3aS,4S,4aR,7aR,8R,9aR)-3,3a,4,4a,7a,8,9,9a-Octahydro-4-hydroxy-4a,8-dimethyl-3-methyleneazuleno[6,5-b]furan-2,5-dione
  • (3aS,4S,4aR,7aR,8R,9aR)-4-hydroxy-4a,8-dimethyl-3-methylidene-3,3a,4,4a,7a,8,9,9a-octahydroazuleno[6,5-b]furan-2,5-dione
  • 6alpha,8beta-Dihydroxy-4-oxoambrosa-2,11(13)-dien-12-oic acid 12,8-lactone
  • Ambrosa-2,11(13)-dien-12-oic acid, 6-alpha,8-beta-dihydroxy-4-oxo-, 12,8-lactone
  • Ambrosa-2,11(13)-dien-12-oic acid, 6alpha,8beta-dihydroxy-4-oxo-, 12,8-lactone
  • Ambrosa-2,11(13)-dien-12-oic acid, 6alpha,8beta-dihydroxy-4-oxo-, 12,8-lactone (8CI)
  • Ambrosa-2,11(13)-dien-12-oic acid, 6α,8β-dihydroxy-4-oxo-, 12,8-lactone
  • Azuleno(6,5-b)furan-2,5-dione, 3,3a,4,4a,7a,8,9,9a-octahydro-4-hydroxy-4a,8-dimethyl-3-methylene-, (3aS-(3aalpha,4alpha,4abeta,7aalpha,8alpha,9aalpha))-
  • Azuleno(6,5-b)furan-2,5-dione, 3,3a,4,4a,7a,8,9,9a-octahydro-4-hydroxy-4a,8-dimethyl-3-methylene-, (3aS-(3aalpha,4alpha,4abeta,7aalpha,8alpha,9aalpha))- (9CI)
  • Azuleno[6,5-b]furan-2,5-dione, 3,3a,4,4a,7a,8,9,9a-octahydro-4-hydroxy-4a,8-dimethyl-3-methylene-, (3aS,4S,4aR,7aR,8R,9aR)-
  • See more synonyms
Sort by
Found 4 products.
  • Helenalin
    TLC
    + Info

    Helenalin

    CAS:
    Formula:C15H18O4
    Molecular weight:262.31

    Ref: 4Z-H-111

    5mg
    To inquire
    10mg
    To inquire
    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • Helenalin
    Biosynth
    + Info

    Helenalin

    CAS:
    Helenalin is a sesquiterpene lactone, which is a secondary metabolite derived from plants, specifically from the Arnica species. This compound is characterized by its molecular framework containing a cyclodecadiene ring along with an α-methylene-γ-lactone ring, conferring its biological activities. Helenalin exerts its effects primarily by inhibiting key transcription factors such as NF-κB and other molecules involved in critical signaling pathways. This mode of action results from its ability to form adducts with thiol groups of cysteine residues on these proteins, thus altering their activity and inhibiting inflammatory responses. The compound is used widely in biochemical research dedicated to understanding inflammation and cell signaling mechanisms. Due to its potent anti-inflammatory properties, helenalin is often investigated for potential therapeutic applications in conditions such as inflammatory diseases and certain types of cancer. Its ability to modulate immune responses also makes it a compound of interest in immunology and pharmacological studies aiming to design drugs with new anti-inflammatory or anticancer strategies. However, its cytotoxicity needs to be carefully managed when considering any clinical application.
    Purity:Min. 95%

    Ref: 3D-FH177939

    1mg
    959.00€
  • Helenalin
    Targetmol
    + Info

    Helenalin

    CAS:
    Helenalin: anti-inflammatory sesquiterpene, inhibits NF-κB by alkylating p65 cysteine groups, blocks DNA binding.
    Formula:C15H18O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:262.3

    Ref: TM-T15467

    1mg
    To inquire
  • Helenalin
    Glentham
    + Info

    Helenalin

    CAS:
    Formula:C15H18O4
    Purity:≥ 97.0%
    Color and Shape:White to off-white solid
    Molecular weight:262.3

    Ref: 7W-GL2626

    1mg
    643.00€
    500µg
    425.00€