CAS 681482-81-5: Phenol, 4-[4-[4-(trifluoromethoxy)phenoxy]-1-piperidinyl]-

4-(4-(4-(Trifluoromethoxy)phenoxy)piperidin-1-yl)phenol

4-{4-[4-(Trifluoromethoxy)phenoxy]piperidino}benzenol is a hydroquinone derivative that is industrially used as an intermediate for the production of 4-aminophenol and 4-hydroxyphenylacetic acid.

Applications 4-[4-(4-Trifluoromethoxyphenoxy)piperidin-1-yl]phenol is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis. References Sasaki, H., et al.: J. Med. Chem., 49, 7854 (2006);