CAS 68401-05-8: (2S)-2-[5-[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]-2,4-dihydroxyphenyl]-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one

Kuwanon E blocks cholinesterase; K i 3.1-37.5 μM for AChE, 1.7-19.1 μM for BChE; stops MUC5AC production in NCI-H292 cells.

Kuwanon E is a natural compound, specifically a flavonoid, derived from the root bark of the mulberry tree, Morus alba. As a bioactive component, Kuwanon E exhibits significant antioxidant and anti-inflammatory effects. Its mechanism of action involves the scavenging of free radicals and the inhibition of inflammatory pathways, which contributes to its therapeutic potential. Kuwanon E has been investigated for various applications in scientific research, particularly in the fields of pharmacology and medicine. Its antioxidant properties make it a candidate for studies aimed at reducing oxidative stress-related damage in cells, while its anti-inflammatory effects have garnered interest for potential use in managing inflammatory diseases. Additionally, Kuwanon E is being explored for its antitumor activities, making it a subject of interest in cancer research. The compound's diverse pharmacological activities suggest its potential utility in developing therapeutic agents targeting various pathological conditions.