1-Methyl-6-nitro-1H-indazole is a chemical compound characterized by its indazole core, which is a bicyclic structure containing a five-membered ring fused to a six-membered ring. The presence of a methyl group at the 1-position and a nitro group at the 6-position contributes to its unique chemical properties. This compound is typically a yellow to orange solid and is known for its potential applications in medicinal chemistry and as a building block in organic synthesis. It exhibits moderate solubility in organic solvents, which can vary depending on the solvent's polarity. The nitro group is a strong electron-withdrawing group, influencing the compound's reactivity and stability. Additionally, 1-Methyl-6-nitro-1H-indazole may exhibit biological activity, making it of interest in pharmacological research. As with many nitro-containing compounds, it is important to handle it with care due to potential toxicity and environmental concerns. Proper safety protocols should be followed when working with this substance in a laboratory setting.

1-Methyl-6-nitro-1H-indazole

6850-23-3: 1-Methyl-6-nitroindazole, 1H-indazole, 1-methyl-6-nitro-, NSC 131654, 1-Methyl-6-nitro-1H-indazole

1-Methyl-6-nitro-1H-indazole is a triethyloxonium cation with substructures that are important for its anti-leishmanial activity. The molecule is hydrophobic and has a statistically significant effect on endpoints in vitro. It has been shown to be an efficient inhibitor of Leishmania amazonensis, which causes leishmaniasis. This compound also has anti-inflammatory properties and may be useful in the treatment of cancer. 1-Methyl-6-nitro-1H-indazole was synthesized by reacting methyl iodide with nitrobenzene, followed by reduction with sodium borohydride. Crystal x ray diffraction techniques and heterogeneous phase studies were used to characterize this compound.

CAS 6850-23-3: 1-Methyl-6-nitro-1H-indazole

1-Methyl-6-nitro-1H-indazole

Ref: 3D-FM29227

1-Methyl-6-nitro-1H-indazole

Ref: IN-DA005PSJ

1-Methyl-6-nitro-1H-indazole

Ref: 10-F217476

1-Methyl-6-nitro-1H-indazole

Ref: 54-OR110173