CAS 6856-01-5: 2-Butenoic acid, 4-hydroxy-2-(hydroxymethyl)-, (3aR,4R,6E,10E,11aR)-2,3,3a,4,5,8,9,11a-octahydro-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester, (2E)-

Eupatoriopicrin: Anti-trypanosomal, cytotoxic to T. brucei rhodesiense, can damage DNA, weakly sensitizes guinea pigs.

Eupatoriopicrin is a sesquiterpene lactone, which is an intricate class of naturally occurring organic compounds. It is derived from plants, particularly in the Asteraceae family, such as those belonging to the Eupatorium genus. Eupatoriopicrin exhibits its mode of action primarily through the alkylation of biological nucleophiles, which can disrupt normal cellular processes. This mechanism makes it a compound of interest for its potential as an inhibitor of various biological pathways, particularly those involved in inflammation and cancer. In scientific research, eupatoriopicrin has been investigated for its antiproliferative and cytotoxic properties, revealing promise in suppressing cancer cell lines. Furthermore, its ability to modulate immune responses and exhibit anti-inflammatory effects has sparked interest in its application in immunological studies. While not yet a mainstream therapeutic agent, eupatoriopicrin's complex molecular structure and bioactivity serve as a foundation for further investigation into its potential roles in pharmacology and phytochemistry. Researchers continue to explore its possible applications in developing novel therapeutic strategies.