CAS: 69097-99-0

Oxygen-heterocyclic compound

(+/-)-Hesperetin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

(Rac)-Hesperetin, a racemic flavanone, inhibits human UGT activity and triggers apoptosis via p38 MAPK activation.

Hesperetin

Hesperetin is a flavonoid compound, which is naturally derived from citrus fruits such as oranges and lemons. As a notable bioactive molecule, its mode of action primarily involves the modulation of oxidative stress and inflammatory pathways. Hesperetin exerts its effects by scavenging free radicals and inhibiting the activation of inflammatory cytokines, making it a compound of significant interest in the biochemical and pharmacological sectors. The uses and applications of hesperetin are diverse, encompassing research into cardiovascular health, cancer prevention, and protection against neurodegenerative disorders. It is frequently investigated for its potential to improve vascular function, reduce blood pressure, and lower cholesterol levels. Furthermore, its anti-inflammatory effects are studied in the context of arthritis and other inflammatory diseases. Hesperetin's neuroprotective properties also suggest potential therapeutic applications in conditions such as Alzheimer's and Parkinson’s disease, where oxidative stress plays a critical pathological role.

Applications rac-Hesperetin is a derivative of Hesperidine (H281185) with potential antihyperglycemic activity. References Zhang, B., et al.: Bioorg. Med. Chem. Lett., 22, 7194 (2012)