CAS 694-05-3: 1,2,3,6-Tetrahydropyridine

Applications 1,2,3,6-Tetrahydropyridine (cas# 694-05-3) is a useful research chemical. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

1,2,3,6-Tetrahydropyridine is an experimental drug that acts as a dopamine receptor antagonist. It has been shown to induce neuronal death in the presence of excess dopamine by inhibiting the uptake of dopamine by neurons. The nitrogen atom in position 6 may be involved in binding to the receptor and initiating the conformational change needed for activation. Tetrahydropyridine binds to the D1 and D2 receptors with high affinity, but it does not bind to D4 receptors. Tetrahydropyridine can also inhibit locomotor activity in mice and rats.

1,2,3,6-Tetrahydropyridine