2'-TBDMS-Bz-rA, also known as 2'-O-(tert-butyldimethylsilyl)-benzoyl-adenosine, is a modified nucleoside that features a benzoyl group and a tert-butyldimethylsilyl (TBDMS) protecting group at the 2' position of the ribose sugar. This compound is primarily used in nucleic acid chemistry, particularly in the synthesis of RNA oligonucleotides, where it serves to enhance stability and facilitate the manipulation of RNA structures. The TBDMS group provides protection against hydrolysis, while the benzoyl moiety can enhance the solubility and reactivity of the nucleoside. The presence of these modifications allows for improved handling during chemical reactions and can influence the overall properties of the resulting RNA molecules, such as their stability and binding affinity. Additionally, the compound is characterized by its ability to participate in various chemical reactions typical of nucleosides, including phosphorylation and coupling reactions, making it a valuable tool in synthetic biology and medicinal chemistry applications.

2'-TBDMS-Bz-rA

69504-07-0: N6-benzoyl-2'-O-(tert-butyldiMethylsilyl)adenosine

N6-benzoyl-2'-O-(tert-butyldiMethylsilyl)adenosine

N6-Benzoyl-2'-O-tert-butyldimethylsilyladenosine (BTS) is a novel phosphoramidate monophosphate nucleoside analog that has been modified to be resistant to the ribonuclease A enzyme. BTS is an activator of DNA synthesis and inactivator of RNA synthesis, which makes it useful for the treatment of cancer and antiviral infections. This drug is synthesized using high quality reagents and can be used for the production of phosphoramidites to produce high purity oligonucleotides.

CAS 69504-07-0: 2'-TBDMS-Bz-rA

N6-benzoyl-2'-O-(tert-butyldiMethylsilyl)adenosine

Ref: IN-DA00FGDF

N6-Benzoyl-2'-O-tert-butyldimethylsilyladenosine

Ref: 3D-NT57542

N-(9-((2R,3R,4R,5R)-3-((tert-Butyldimethylsilyl)oxy)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide

Ref: 10-F982761