(1R,2R)-2-aminocyclohexanol is a chiral amine characterized by its cyclohexane ring structure with an amino group and a hydroxyl group attached to adjacent carbon atoms. This compound is typically a colorless to pale yellow liquid or solid, depending on its form and purity. It exhibits both basic and alcohol functionalities, making it a versatile intermediate in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. The presence of the amino group allows for hydrogen bonding, which can influence its solubility in polar solvents, while the cyclohexanol moiety contributes to its hydrophobic characteristics. As a chiral compound, it can exist in two enantiomeric forms, with (1R,2R) indicating the specific spatial arrangement of its substituents, which is crucial for its biological activity. This compound is also of interest in asymmetric synthesis and catalysis due to its potential to act as a chiral auxiliary or ligand. Safety data should be consulted for handling and storage, as with all chemical substances.

(1R,2R)-2-aminocyclohexanol

6982-39-4: cyclohexanol, 2-amino-, (1R,2R)-, x

trans-2-Amino-cyclohexanol

rac-(1R,2R)-2-aminocyclohexan-1-ol, trans

Trans-2-aminocyclohexanol is a chemical compound that has been shown to have anticancer activity. It possesses the ability to inhibit the growth of tumor cells in vitro and in vivo by inhibiting the synthesis of DNA, RNA, and protein. Trans-2-aminocyclohexanol also inhibits the production of nitric oxide (NO), which is involved in tumor cell proliferation. The cytotoxic effect of this drug is pH dependent, with an acidic pH being needed for its anticancer activity. This compound has been isolated from potassium ion solutions at low concentration yields using magnetic resonance spectroscopy (NMR). Trans-2-aminocyclohexanol has a protonated amine group that can form hydrogen bonds with other molecules, which may explain its ability to interact with DNA.

CAS 6982-39-4: (1R,2R)-2-aminocyclohexanol

trans-2-Amino-cyclohexanol

Ref: 54-OR307600

rac-(1R,2R)-2-aminocyclohexan-1-ol, trans

Ref: IN-DA00FE9V

Trans-2-Aminocyclohexanol

Ref: 3D-FT137541