CAS 70563-58-5: Herbimycin A
Formula:C30H42N2O9
InChI:InChI=1/C30H42N2O9/c1-16-10-9-11-23(37-5)28(41-30(31)36)18(3)12-17(2)27(40-8)24(38-6)13-19(4)26(39-7)21-14-20(33)15-22(25(21)34)32-29(16)35/h9-12,14-15,17,19,23-24,26-28H,13H2,1-8H3,(H2,31,36)(H,32,35)/b11-9-,16-10+,18-12+/t17-,19-,23-,24-,26+,27+,28-/m0/s1
InChI key:InChIKey=MCAHMSDENAOJFZ-BVXDHVRPSA-N
SMILES:O(C)[C@H]1C=2C(=O)C(=CC(=O)C2)NC(=O)/C(/C)=C/C=C\[C@H](OC)[C@@H](OC(N)=O)\C(\C)=C\[C@H](C)[C@@H](OC)[C@@H](OC)C[C@@H]1C
Synonyms:- (15R)-17-Demethoxy-15-methoxy-11-O-methylgeldanamycin
- (4E,6Z,8S,9S,10E,12S,13R,14S,16S,17R)-8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
- (8R,9R,12S,13R,14S,16S,17S)-8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
- (8S,9S,12S,13R,14S,16S,17R)-8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
- 2-Azabicyclo[16.3.1]docosane, geldanamycin deriv.
- 8,13,14,17-Tetramethoxy-4,10,12,16-Tetramethyl-3,20,22-Trioxo-2-Azabicyclo[16.3.1]Docosa-1(21),4,6,10,18-Pentaen-9-Yl Carbamate
- Antibiotic TAN 420F
- Geldanamycin, 17-demethoxy-15-methoxy-11-O-methyl-, (15R)-
- Herbimycin A
- Herbimycin A, Streptomyces sp.
- NSC 305978
- See more synonyms
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Found 6 products.
Herbimycin A, 95%
CAS:A sparingly soluble benzoquinone anti-tumor agent which interacts with the stress induced chaperone protein Hsp90 (heat shock protein 90) This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C30H42N2O9Purity:95%Molecular weight:574.66Herbimycin
CAS:Herbimycin is an antibiotic, which is a natural product derived from Streptomyces bacteria. It functions primarily as a tyrosine kinase inhibitor, disrupting cellular signaling pathways by binding to the ATP-binding site of kinases and inhibiting phosphorylation events. This mode of action makes it an effective tool for scientists studying signal transduction processes and oncogenic transformation. In research applications, Herbimycin is utilized to investigate the role of kinases in various cellular mechanisms, including cancer proliferation and differentiation. Its ability to reversibly inhibit oncogenic kinases has made it a valuable agent in exploring therapeutic strategies against cancer. By providing insights into kinase function, it assists in elucidating pathways critical for cell growth and survival. Herbimycin's selective action against certain cellular processes makes it a key resource in the examination of molecular pathways and the potential development of targeted therapies.Formula:C30H42N2O9Purity:Min. 95%Molecular weight:574.66 g/molHerbimycin A
CAS:Formula:C30H42N2O9Purity:91.5%Color and Shape:Bright yellow. PowderMolecular weight:574.0
