4,4,4-Trifluorocrotonic acid is an organic compound characterized by its unique trifluoromethyl group and a conjugated double bond system. It is a derivative of crotonic acid, featuring three fluorine atoms attached to the carbon adjacent to the carboxylic acid functional group. This substitution significantly influences its chemical properties, including increased acidity and altered reactivity compared to its non-fluorinated counterparts. The presence of the trifluoromethyl group enhances its lipophilicity and may affect its solubility in various solvents. 4,4,4-Trifluorocrotonic acid is typically a colorless to pale yellow liquid or solid, depending on temperature and purity. It is used in organic synthesis and may serve as an intermediate in the production of pharmaceuticals and agrochemicals. Additionally, its unique structure allows for potential applications in materials science and as a building block in fluorinated compounds. Safety precautions should be observed when handling this compound, as it may pose health risks due to its fluorinated nature.

4,4,4-Trifluorocrotonic acid

71027-02-6: (2E)-4,4,4-Trifluoro-2-butenoic acid, (2E)-4,4,4-Trifluorobut-2-enoic acid, 2-Butenoic acid, 4,4,4-trifluoro-, (2E)-, 2-Butenoic acid, 4,4,4-trifluoro-, (E)-

2-Butenoic acid, 4,4,4-trifluoro-

Trifluorocrotonic acid is a reactive compound that is used as a modifier in organic synthesis. It has been shown to be an active ingredient in the treatment of helminth infections. Research has shown that trifluorocrotonic acid can be converted to 4-hydroxy-3,5-dimethylpyrrole by reaction with amines. This conversion produces ethyl esters, which are isomers of crotonic acid. Trifluorocrotonic acid can also react with toll-like receptor 2 (TLR2) and its ligand lipopolysaccharide (LPS). The result of this reaction is the production of cytokines and chemokines that stimulate cells such as macrophages or neutrophils, which help fight against cancer cells or infections.

CAS 71027-02-6: 4,4,4-Trifluorocrotonic acid

4,4,4-Trifluorocrotonic acid

Ref: 54-PC3392

4,4,4-Trifluorocrotonic acid

Ref: 10-F005350

2-Butenoic acid, 4,4,4-trifluoro-

Ref: IN-DA00IC4K

4,4,4-Trifluorocrotonic acid

Ref: 3D-FT78887