2-(4-Methylquinazolin-2-yl)guanidine, with the CAS number 716-11-0, is an organic compound characterized by its unique structure that combines a quinazoline moiety with a guanidine functional group. This compound typically appears as a solid and is known for its potential biological activity, particularly in medicinal chemistry. The presence of the quinazoline ring contributes to its pharmacological properties, as quinazolines are often associated with various biological activities, including anti-cancer and anti-inflammatory effects. The guanidine group enhances its basicity and can influence its interaction with biological targets. Solubility can vary depending on the solvent, but it is generally more soluble in polar solvents. The compound's reactivity is influenced by the functional groups present, making it a candidate for further chemical modifications. Overall, 2-(4-methylquinazolin-2-yl)guanidine is of interest in research for its potential applications in drug development and as a tool in biochemical studies.

2-(4-methylquinazolin-2-yl)guanidine

716-11-0: guanidine, N-(4-methyl-2-quinazolinyl)-

N-(4-methylquinazolin-2-yl)guanidine

N-(4-Methylquinazolin-2-yl)guanidine (NQG) is a GABA receptor agonist that has been shown to have low potency. It binds to the alpha1 subunit of the GABA receptor and enhances its activity, thereby increasing the frequency of cycles in the activated state. NQG has been shown to be effective as a pharmacological agent for treating congestive heart failure and influenza virus infection. NQG also has an antagonistic effect on growth factor receptors, inhibiting their activity. This may be due to its ability to inhibit the release of gamma-aminobutyric acid (GABA).

CAS 716-11-0: 2-(4-methylquinazolin-2-yl)guanidine

N-(4-methylquinazolin-2-yl)guanidine

Ref: 10-F372606

N-(4-Methylquinazolin-2-yl)guanidine

Ref: 3D-FM129935

1-(4-Methylquinazolin-2-yl)guanidine

Ref: 54-OR303178