CAS 71827-03-7: Ivermectin B1a
Formula:C48H74O14
InChI:InChI=1S/C48H74O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,19,25-26,28,30-31,33-45,49-50,52H,11,16-18,20-24H2,1-10H3/b13-12+,27-15+,32-14+/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1
InChI key:InChIKey=AZSNMRSAGSSBNP-XPNPUAGNSA-N
SMILES:O[C@]/12[C@@]3(OC\C1=C/C=C/[C@H](C)[C@H](O[C@H]4C[C@H](OC)[C@@H](O[C@H]5C[C@H](OC)[C@@H](O)[C@H](C)O5)[C@H](C)O4)\C(\C)=C\C[C@@]6(C[C@](OC(=O)[C@@]2(C=C(C)[C@H]3O)[H])(C[C@]7(O6)O[C@]([C@H](CC)C)([C@@H](C)CC7)[H])[H])[H])[H]
Synonyms:- (2aE,4E,5'S,6S,6'R,8E,11R,13R,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-5',6,8,19-tetramethyl-6'-[(1S)-1-methylpropyl]-17-oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl (4xi)-2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-3-O-methyl-α-L-threo-hexopyranoside
- 22,23-Dihydro-5-O-demethylavermectin A1a
- 22,23-Dihydroavermectin B(1)a
- 22,23-Dihydroavermectin B1a
- 22,23-Dihydroavermectin B<sub>1a</sub>
- 5-O-Demethyl-22,23-dihydroavermectin A<sub>1a</sub>
- Avermectin A1a, 22,23-dihydro-5-O-demethyl-
- Avermectin A<sub>1a</sub>, 5-O-demethyl-22,23-dihydro-
- Brn 4643153
- Dihydroavermectin B1a
- Dihydroavermectin B<sub>1a</sub>
- See more synonyms
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Found 8 products.
Ivermectin B1a-d2
CAS:Formula:C48H72D2O14Color and Shape:White To Off-White SolidMolecular weight:877.12Ivermectin B1a-D2
CAS:Controlled ProductApplications Ivermectin B1a-D2 is a deuterium labelled analogue of Ivermectin B1a (I940815), which is a major component of Ivermectin (I940800), a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An invitro inhibitor of SARS-CoV-2/ Covid-19. References Chabala, J.C., et al.: J. Med. Chem., 23, 1134 (1980); Campbell, W.C., et al.: Science, 221, 823 (1983); Bennett, J.L., et al.: Parasitol. Today, 4, 226 (1988); Plaisier, A.P., et al.: J. Infect. Dis., 172, 204 (1995);; Caly, L., et al.: Antivir. Res., 178Formula:C48H72D2O14Color and Shape:NeatMolecular weight:877.11Ivermectin B1a (>85%)
CAS:Controlled ProductApplications Ivermectin B1a is a major component of Ivermectin (I940800), a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An invitro inhibitor of SARS-CoV-2/ Covid-19. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Chabala, J.C., et al.: J. Med. Chem., 23, 1134 (1980); Campbell, W.C., et al.: Science, 221, 823 (1983); Bennett, J.L., et al.: Parasitol. Today, 4, 226 (1988); Plaisier, A.P., et al.: J. Infect. Dis., 172, 204 (1995);; Caly, L., et al.: Antivir. Res., 178Formula:C48H74O14Purity:>85%Color and Shape:White To Off-WhiteMolecular weight:875.09Ivermectin B1a
CAS:Ivermectin B1a is the major (80%) component of commercially available ivermectin and a derivative of Avermectin B1a.Formula:C48H74O14Purity:≥98%Color and Shape:SolidMolecular weight:875.09Ivermectin B1a-D2
CAS:Ivermectin is a broad-spectrum antiparasitic agent that is used to treat onchocerciasis and other infectious diseases. It binds selectively to gamma-aminobutyric acid (GABA) receptors in the central nervous system and inhibits the release of neurotransmitters, thereby inhibiting the inflammatory response. Ivermectin has been shown to be safe for use in humans and has a long half-life that allows for once-weekly administration. This drug also has pharmacokinetic properties that are similar among different species and clinical studies have shown no significant differences between human and animal models. Ivermectin is applied topically as an ointment or cream or orally as tablets or capsules, depending on the condition being treated.Formula:C48H72D2O14Purity:Min. 95%Molecular weight:877.11 g/mol
