3-Chloro-4-methylpyridine is a heterocyclic organic compound characterized by a pyridine ring substituted with a chlorine atom at the 3-position and a methyl group at the 4-position. Its molecular formula is C6H6ClN, and it features a nitrogen atom within the aromatic ring, contributing to its basicity and reactivity. This compound typically appears as a colorless to pale yellow liquid with a distinctive odor. It is soluble in organic solvents and exhibits moderate solubility in water. 3-Chloro-4-methylpyridine is primarily used in the synthesis of various pharmaceuticals and agrochemicals, as well as in research applications. The presence of the chlorine atom enhances its electrophilic properties, making it a useful intermediate in chemical reactions. Safety considerations include handling it in a well-ventilated area and using appropriate personal protective equipment, as it may pose health risks upon exposure. Overall, 3-Chloro-4-methylpyridine is an important compound in organic synthesis with diverse applications in the chemical industry.

3-Chloro-4-methylpyridine

72093-04-0: 3-Chloro-4-picoline, 4-Picoline, 3-chloro-, Pyridine, 3-Chloro-4-Methyl-, 3-Chloro-4-methylpyridine

C3-Chloro-4-methylpyridine is an intermediate in the synthesis of tofacitinib, a drug used to treat rheumatoid arthritis. C3-Chloro-4-methylpyridine is prepared by asymmetric hydrogenation of 3,5-dichloro-2,6-dimethylaniline. This process proceeds through an acylation step followed by an asymmetric hydrogenation. The reaction mixture consists of the desired product and a significant amount of 3,5 dichloropyridine. The desired product can be isolated from this mixture using column chromatography or recrystallization.

CAS 72093-04-0: 3-Chloro-4-methylpyridine

3-Chloro-4-methylpyridine

Ref: 54-OR345131

3-Chloro-4-methylpyridine

Ref: 10-F078033

c3-Chloro-4-methylpyridine

Ref: 3D-FC33804

3-Chloro-4-Methylpyridine

Ref: IN-DA0033NW