CAS 722-92-9: 4-(hexafluoro-2-hydroxyisopropyl)aniline

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

2-(4-Aminophenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol

4-Amino-A,alpha-Bis(Trifluoromethyl)-Benzenemethanol is a crystallized compound that yields the title compound as white crystals. It is soluble in water and hydrolyzes to give the hydrochloride salts of 4-amino-a,alpha-bis(trifluoromethyl)benzene methanol and trifluoroacetic acid. The reaction sequence is optimized using aluminum chloride as a reagent. The reaction time ranges from 12 hours to 48 hours. Friedel-Crafts reactions are often used to make chlorinated aromatic compounds such as 4-amino-a,alpha-bis(trifluoromethyl)benzene methanol and trifluoroacetic acid. Chlorination can be achieved by adding Cl2 gas or Cl2 in liquid form to the aromatic compound in a flask containing AlCl3 (aluminum chloride). Tr