CAS: 72715-02-7

Pinocembrin, Ilicol inhibit root growth: IC50s of 0.199-7.69mM, 1.22-8.07mM for P.miliaceum, A.sativa, L.sativa, R.sativus; non-mutagenic to Allium cepa cells.

Ilicol is an antibiotic compound, which is derived from the bacterial genus Streptomyces with a specific mode of action targeting fungal cell structures. Streptomyces species are well-known for their role as prolific producers of a diverse array of bioactive compounds, including antibiotics. Ilicol functions by disrupting the integrity of fungal cell membranes, leading to compromised cellular homeostasis, eventually resulting in cell lysis and death. Ilicol is utilized primarily in the field of medical microbiology and agricultural science for its antifungal properties. It is employed in experimental studies aiming to elucidate mechanisms of fungal resistance, as well as in developing strategies for controlling pathogenic fungi affecting crops. Researchers also investigate its potential applications in clinical settings, where antifungal resistance poses a significant challenge. The compound's activity profile and efficacy are subjects of ongoing investigations to better understand its potential utility across diverse biological systems.