CAS 72803-02-2: Darodipine
Formula:C19H21N3O5
InChI:InChI=1S/C19H21N3O5/c1-5-25-18(23)14-10(3)20-11(4)15(19(24)26-6-2)16(14)12-8-7-9-13-17(12)22-27-21-13/h7-9,16,20H,5-6H2,1-4H3
InChI key:InChIKey=QERUYFVNIOLCHV-UHFFFAOYSA-N
SMILES:C(OCC)(=O)C=1C(C(C(OCC)=O)=C(C)NC1C)C=2C=3C(C=CC2)=NON3
Synonyms:- 2,1,3-Benzoxadiazole, 3,5-pyridinedicarboxylic acid deriv.
- 3,5-Pyridinedicarboxylic acid, 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-, 3,5-diethyl ester
- 3,5-Pyridinedicarboxylic acid, 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-, diethyl ester
- 3,5-Pyridinedicarboxylic acid, 4-(4-benzofurazanyl)-1,4-dihydro-2,6-dimethyl-, diethyl ester
- Darodipine [USAN:INN]
- Darodipino
- Darodipino [Spanish]
- Darodipinum
- Darodipinum [Latin]
- Dazodipin
- Diethyl 4-(2,1,3-Benzoxadiazol-4-Yl)-2,6-Dimethyl-1,4-Dihydropyridine-3,5-Dicarboxylate
- See more synonyms
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Found 4 products.
Darodipine
CAS:Darodipine (PY-108068) is a dihydropyridine type Ca+2 antagonist.Formula:C19H21N3O5Purity:99.25%Color and Shape:SolidMolecular weight:371.39Darodipine
CAS:Controlled ProductApplications Darodipine, is a calcium channel antagonist. References Matucci, R., et al.: British J. Pharmacol., 122, 1353 (1997);Formula:C19H21N3O5Color and Shape:NeatMolecular weight:371.39Darodipine
CAS:Darodipine is a calcium channel blocker, which is derived from dihydropyridine compounds. Its primary mode of action involves the inhibition of voltage-gated calcium channels in the smooth muscle cells of the vascular system. By preventing calcium influx, Darodipine leads to reduced contraction of the vascular smooth muscle, resulting in vasodilation and decreased vascular resistance. The reduced vascular resistance translates into lower blood pressure, making Darodipine valuable in the management of hypertension. Its specificity for vascular smooth muscle over cardiac muscle channels reduces the risk of cardiac side effects commonly associated with non-selective calcium channel blockers. This pharmacological specificity is achieved through its high lipophilicity, which facilitates membrane penetration and selective action at the arterial smooth muscle. Reflecting its potential and targeted effects, Darodipine finds application primarily in clinical settings focused on cardiovascular health, notably in patients diagnosed with hypertension. Its efficacy in reducing arterial pressure, while maintaining a favorable side effect profile, positions it as an effective treatment option for managing chronic hypertension and related cardiovascular conditions.Formula:C19H21N3O5Purity:Min. 95%Molecular weight:371.4 g/mol
