2'-Deoxy-8-(9H-fluoren-2-ylamino)guanosine is a modified nucleoside that features a guanosine backbone with a 9H-fluoren-2-ylamino group attached at the 8-position of the purine ring. This modification can influence the molecule's properties, such as its solubility, stability, and interaction with nucleic acids. The presence of the fluorenyl group may enhance the compound's ability to intercalate into DNA or RNA structures, potentially affecting its biological activity. As a nucleoside analog, it may be of interest in research related to nucleic acid chemistry, drug design, and molecular biology. The compound is characterized by its ability to participate in hydrogen bonding and π-π stacking interactions, which are crucial for its potential applications in therapeutic contexts. Additionally, its unique structure may provide insights into the mechanisms of nucleic acid recognition and the development of novel antiviral or anticancer agents. Overall, 2'-deoxy-8-(9H-fluoren-2-ylamino)guanosine represents a significant compound for further exploration in biochemical research.

2'-deoxy-8-(9H-fluoren-2-ylamino)guanosine

73051-69-1: Guanosine, 2'-deoxy-8-(9H-fluoren-2-ylamino)-, N-(2′-Deoxyguanosin-8-yl)-2-aminofluorene, N-(Deoxyguanosin-8-yl)-2-aminofluorene, N-(Deoxyguanosine-C8-yl)-2-aminofluorene

2'-Deoxy-8-(9H-fluoren-2-ylamino)-guanosine (FdA) is a synthetic nucleoside that was designed for use as a dietary supplement to inhibit carcinogenesis. It is an analog of guanosine and is phosphorylated by cellular kinases to form 2'-deoxy-8-(9H-fluoren-2-ylamino)-inosine monophosphate. FdA inhibits the process of DNA replication in mammalian cells, which may be due to its ability to bind single stranded DNA. This drug has been shown to reduce the mutation frequency and increase the life span of mice with bladder cancer.

CAS 73051-69-1: 2'-deoxy-8-(9H-fluoren-2-ylamino)guanosine

2'-Deoxy-8-(9H-fluoren-2-ylamino)-guanosine

Ref: 3D-ND10433

2’-Deoxy-8-(9H-fluoren-2-ylamino)-guanosine

Ref: TR-D232930