CAS 73069-14-4: Atractylenolide II
Formula:C15H20O2
InChI:InChI=1S/C15H20O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h12-13H,1,4-8H2,2-3H3/t12-,13-,15+/m0/s1
InChI key:InChIKey=OQYBLUDOOFOBPO-KCQAQPDRSA-N
SMILES:C[C@]12[C@@](CC=3[C@](C1)(OC(=O)C3C)[H])(C(=C)CCC2)[H]
Synonyms:- (4aS,8aR,9aS)-3,8a-Dimethyl-4-methylene-4a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(4H)-one
- (4aS,8aR,9aS)-3,8a-dimethyl-4-methylidene-4a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(4H)-one
- (4aS,8aR,9aS)-4a,5,6,7,8,8a,9,9a-Octahydro-3,8a-dimethyl-5-methylenenaphtho[2,3-b]furan-2(4H)-one
- 2-Atractylenolide
- Asterolide
- Eudesma-4(15),7(11)-dien-8α,12-olide
- Naphtho[2,3-b]furan-2(4H)-one, 4a,5,6,7,8,8a,9,9a-octahydro-3,8a-dimethyl-5-methylene-, (4aS,8aR,9aS)-
- Naphtho[2,3-b]furan-2(4H)-one, 4a,5,6,7,8,8a,9,9a-octahydro-3,8a-dimethyl-5-methylene-, [4aS-(4aα,8aβ,9aβ)]-
- naphtho[2,3-b]furan-2(4H)-one, 4a,5,6,7,8,8a,9,9a-octahydro-3,8a-dimethyl-4-methylene-, (4aS,8aR,9aS)-
- Atractylenolide II
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Found 7 products.
Atractylenolide ii
CAS:LactoneFormula:C15H20O2Purity:≥ 95.0 % (HPLC)Color and Shape:PowderMolecular weight:232.32Atractylenolide II
CAS:Atractylenolide II has antiinflammatory activity, it can inhibit platelets activities and thrombus formation. Atractylenolide II has cytotoxic/apoptotic effects may via p38 activation ,ERK and Akt inactivation, p53 dependent, it also has antimelanoma effect by inhibiting STAT3 signalling.Formula:C15H20O2Purity:95%~99%Molecular weight:232.323AtractylenolideII
CAS:Atractylenolide II is a sesquiterpenoid lactone, which is primarily isolated from the medicinal herb Atractylodes lancea. This compound is a naturally occurring secondary metabolite found in the root of the plant, a source well-regarded in traditional Chinese medicine. Atractylenolide II exerts its effects through various biological mechanisms, including modulation of the immune response, anti-inflammatory activity, and inhibition of certain signaling pathways that contribute to cellular proliferation and inflammation. In-depth studies have revealed its efficacy in modulating the NF-kB and MAPK signaling pathways, which play critical roles in inflammation and immune response. These molecular actions make Atractylenolide II a compound of interest in the research of anti-inflammatory and immunomodulatory therapies. The compound has been investigated for its potential applications in treating conditions such as inflammatory diseases, cancer, and metabolic disorders, offering a promising avenue for the development of new therapeutic agents. Scientists continue to explore its pharmacokinetics and mechanisms of action to fully harness its therapeutic potential in clinical settings.Formula:C15H20O2Purity:Min. 95%Molecular weight:232.32 g/molAtractylenolide II
CAS:Atractylenolide II inhibits STAT3, activates p38, deactivates ERK/Akt, and induces p53-dependent cytotoxicity against melanoma.Formula:C15H20O2Purity:99.64% - 99.89%Color and Shape:SolidMolecular weight:232.32
