CAS 73069-25-7: Praeruptorin A
Formula:C21H22O7
InChI:InChI=1/C21H22O7/c1-6-11(2)20(24)27-19-18(25-12(3)22)16-14(28-21(19,4)5)9-7-13-8-10-15(23)26-17(13)16/h6-10,18-19H,1-5H3/b11-6-/t18-,19-/m1/s1
SMILES:C/C=C(/C)\C(=O)O[C@@H]1[C@@H](c2c(ccc3ccc(=O)oc23)OC1(C)C)OC(=O)C
Synonyms:- (-)-Pareruptorin A
- Ccris 7247
- (9R,10R)-10-(acetyloxy)-8,8-dimethyl-2-oxo-9,10-dihydro-2H,8H-pyrano[2,3-f]chromen-9-yl (2Z)-2-methylbut-2-enoate
- (+-)-Praeruptorin A
- (+)-praeruptorin A
Sort by
Found 6 products.
DL-Praeruptorin A
CAS:Praeruptorin A exerts neuroprotective, anti-osteoclastogenic, anti-inflammatory, distinct relaxant effects, it is beneficial to facilitate nestin expression in myocarditis,and suitable in treatment of early myocarditis. Praeruptorin A can significantly up-regulate UGT1A1 expression in HepG2 cells partially via the CAR-mediated pathway. Praeruptorin A inhibited p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca2+ oscillation.Formula:C21H22O7Purity:95%~99%Molecular weight:386.4(±)-Praeruptorin A
CAS:(±)-Praeruptorin A could exhibit its anti-osteoclastogenic activity by inhibiting p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca(2+) oscillation.Formula:C21H22O7Purity:98.9% - 99.73%Color and Shape:SolidMolecular weight:386.4Praeruptorin A
CAS:Formula:C21H22O7Purity:99%Color and Shape:SolidMolecular weight:386.39517999999987Praeruptorin A
CAS:Applications Praeruptorin A is used in the treatment of cardiac diseases, extracted from Peucedani Radix, it exhibits anti-hypertensive effects. Also a potential anti-tumor agent due to the ability to modulate P-glycoprotein (Pgp), overexpression in MDR tumor cells. References Song, Y. et al.: Molecules, 17, 4236 (2012); Shen, X. et al.: J. Pharm. Pharmacol., 64 90 (2012);Formula:C21H22O7Color and Shape:NeatMolecular weight:386.40
