CAS: 73210-81-8

Ferruginin A is a marine-derived compound, classified as a natural iron chelator. It is isolated from various marine organisms, particularly sponges and seaweeds, known for their complex secondary metabolites. As an iron chelator, Ferruginin A functions by binding to free iron ions in biological systems, thereby reducing oxidative stress and preventing metal-catalyzed radical formation. This action is crucial, particularly in cellular environments where excess free iron can lead to detrimental oxidative damage. Ferruginin A's primary applications are within the field of neuroprotective research, where iron dysregulation is implicated in neurodegenerative diseases such as Alzheimer's and Parkinson's. By modulating iron homeostasis, Ferruginin A can provide insights into therapeutic strategies aimed at mitigating oxidative damage in neuronal cells. Additionally, its role in exploring the pathology of these diseases makes it a valuable tool for scientists investigating the intricate balance of metal ions in the human brain. As part of a broader quest to understand neurodegeneration, Ferruginin A aids in unraveling the complex interplay between molecular structures and their physiological impacts.