CAS 7355-22-8: 5-Bromo-&sect

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5-Bromo-2,4-Dihydroxybenzoic Acid

5-Bromo-2,4-dihydroxybenzoic acid is an organic compound that is found in plants and animals. It is a metabolite of benzoic acid and can be produced by the metabolism of phenylalanine. 5-Bromo-2,4-dihydroxybenzoic acid has been shown to inhibit acetylsalicylic acid synthase, which prevents production of the antiinflammatory drug acetylsalicylic acid. This inhibition also leads to a decrease in the production of malonic acid and hippuric acid. The enzyme synthase gene that produces this metabolite can be found on a miniaturized DNA microchip. This gene has been cloned and sequenced by spatially mapping the genes that produce 5-bromo-2,4-dihydroxybenzoic acid using a microchip. Chromatographic analysis has shown that this compound is resistant to some toxins.