CAS 739-27-5: 11-Ketoetiocholanolone

Applications 5beta-Androstan-3alpha-ol-11,17-dione-9,12,12,16,16-d5 is a useful isotopically labeled compound of 11-Oxo Etiocholanolone (O856650)

11-Ketoetiocholanolone is a metabolite of testosterone's excreted metabolite, etiocholanolone, and exhibits anticonvulsant activity[1][2].

Applications A metabolite of Etiocholanolone. References Eriksson, H., et al.: Eur. J. Biochem., 15, 132 (1970), Cook, D., et al.: Endocrinology, 93, 1019 (1973),

11-Oxo etiocholanolone is a steroid hormone that is produced in the adrenal gland. It is a precursor of cortisol and has been shown to have an anti-inflammatory effect, which may be due to its ability to block pro-inflammatory cytokines. 11-Oxo etiocholanolone has also been shown to increase the concentration of cortisol in the blood, which can help treat stress and promote muscle growth. The measurement of 11-oxo etiocholanolone levels in urine and saliva samples may be used as an experimental infection or dietary supplement for women.

11-Oxo etiocholanolone-d4 is a metabolite of testosterone that can be found in the urine. It is used as a dietary supplement for animal health, and has been shown to be effective against experimental infection in a rat model. 11-Oxo etiocholanolone-d4 blocks the production of cortisol by inhibiting an enzyme called 11βHSD2. It also has immunosuppressive effects which may lead to decreased inflammation and enhanced wound healing. The compound is not active against bacteria, but it has been shown to have anti-inflammatory activities in women with urinary tract infections.