Cyclohexanecarbothioamide, with the CAS number 7390-42-3, is an organic compound characterized by the presence of a cyclohexane ring attached to a carbothioamide functional group. This compound typically appears as a colorless to pale yellow solid and is known for its distinctive sulfur-containing functional group, which imparts unique chemical reactivity and properties. Cyclohexanecarbothioamide is soluble in organic solvents, such as ethanol and acetone, but has limited solubility in water due to its hydrophobic cyclohexane structure. The presence of the thiocarbonyl group makes it a potential candidate for various chemical reactions, including nucleophilic additions and condensation reactions. Additionally, it may exhibit biological activity, making it of interest in medicinal chemistry and agricultural applications. Safety precautions should be taken when handling this compound, as it may pose health risks if inhaled or ingested. Overall, cyclohexanecarbothioamide serves as a versatile building block in organic synthesis and research.

Cyclohexanecarbothioamide

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Cyclohexanecarbothioamide is a macrocyclic inhibitor that binds to the active site of phosphatases, which are enzymes that catalyze the hydrolysis of phosphoric acid esters. Cyclohexanecarbothioamide inhibits the activity of two isozymes of phosphatase, protein tyrosine phosphatase-1B (PTP-1B) and protein tyrosine phosphatase-2A (PTP-2A). It has been shown to be a potent inhibitor of insulin resistance in diabetic mice. Cyclohexanecarbothioamide also inhibits fatty acid synthase, an enzyme involved in energy metabolism. This drug has been used for treatment of inflammatory diseases such as rheumatoid arthritis and psoriasis.

CAS 7390-42-3: Cyclohexanecarbothioamide

Cyclohexanecarbothioamide

Ref: 3D-FC131197