CAS: 747413-08-7

VER-50589 is a potent HSP90 inhibitor.

VER-50589

VER-50589 is a broad-spectrum antibiotic, which is synthesized via a semi-synthetic process derived from natural penicillin compounds. This antibiotic exerts its effects predominantly through inhibiting the transpeptidation enzyme essential for bacterial cell wall synthesis. By binding to specific penicillin-binding proteins (PBPs) within the bacterial cell, it disrupts the formation of peptidoglycan cross-links, compromising cell wall integrity and leading to cell lysis. The primary applications of VER-50589 are in the treatment of infections caused by Gram-positive bacteria, including methicillin-resistant strains of Staphylococcus aureus (MRSA). Its highly specific mode of action allows it to target resistant organisms, making it invaluable in clinical settings where conventional antibiotics fall short. Additionally, VER-50589 is employed in research settings to study bacterial resistance mechanisms, offering insights into novel antibiotic development pathways. Scientists continue to investigate its pharmacokinetics and potential combination therapies to enhance efficacy and reduce resistance, emphasizing its role in both therapeutic and experimental contexts.

5-(5-Chloro-2,4-Dihydroxyphenyl)-N-Ethyl-4-(4-Methoxyphenyl)Isoxazole-3-Carboxamide