6-Chloro-5-nitropyridine-3-carboxylic acid is a heterocyclic organic compound characterized by a pyridine ring substituted with a chlorine atom, a nitro group, and a carboxylic acid functional group. The presence of the chlorine atom at the 6-position and the nitro group at the 5-position contributes to its reactivity and potential applications in various chemical syntheses. The carboxylic acid group at the 3-position enhances its solubility in polar solvents and allows for further functionalization. This compound is typically a solid at room temperature and may exhibit moderate to high stability under standard conditions. Its unique structure makes it of interest in pharmaceutical and agrochemical research, particularly in the development of biologically active molecules. Additionally, the compound's properties, such as melting point, boiling point, and solubility, can vary based on the specific conditions and purity of the sample. Safety precautions should be taken when handling this compound, as it may pose health risks due to its chemical nature.

6-chloro-5-nitropyridine-3-carboxylic acid

7477-10-3: 3-Pyridinecarboxylic acid, 6-chloro-5-nitro-, 6-Chloro-5-nitronicotinic acid, 2-Chloro-3-nitro-5-pyridinecarboxylic acid

6-Chloro-5-nitronicotinic acid (6CNA) is a nicotinic acetylcholine receptor agonist that has been synthesized. It is used as an intermediate in the synthesis of other compounds, such as morpholine and acetylcholine. 6CNA binds to the primary amines on the surface of rat brain cells and causes their deamination, which results in the release of nitric oxide (NO). NO activates guanylate cyclase, leading to increased production of cyclic guanosine monophosphate (cGMP). This can lead to smooth muscle relaxation and dilated blood vessels. 6CNA also binds to chloride ions and alkylates them, forming a stable complex with high affinity for chloride ions.

CAS 7477-10-3: 6-chloro-5-nitropyridine-3-carboxylic acid

6-Chloro-5-nitronicotinic acid

Ref: 3D-FC140472

6-Chloro-5-nitronicotinic acid

Ref: IN-DA00337M

6-Chloro-5-nitronicotinic acid

Ref: 54-OR3496

6-Chloro-5-nitronicotinic acid

Ref: 10-F079563