CAS 751-03-1: Obacunone
Formula:C26H30O7
InChI:InChI=1S/C26H30O7/c1-22(2)16-12-17(27)25(5)15(23(16,3)9-7-18(28)32-22)6-10-24(4)19(14-8-11-30-13-14)31-21(29)20-26(24,25)33-20/h7-9,11,13,15-16,19-20H,6,10,12H2,1-5H3/t15-,16+,19+,20-,23-,24+,25+,26-/m1/s1
InChI key:InChIKey=MAYJEFRPIKEYBL-OASIGRBWSA-N
SMILES:C[C@]12[C@]34[C@](O3)(C(=O)O[C@H]([C@]4(C)CC[C@@]1([C@]5(C)[C@@](CC2=O)(C(C)(C)OC(=O)C=C5)[H])[H])C=6C=COC6)[H]
Synonyms:- (1S,3aS,4aR,4bR,6aR,11aR,11bR,13aS)-1-(3-Furanyl)-1,6a,7,11a,11b,12,13,13a-octahydro-4b,7,7,11a,13a-pentamethyloxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aH,4bH,6H)-trione
- (5aR,5bR,7aS,8R,10aS,11aR,11bR,13aR)-8-(furan-3-yl)-1,1,5a,7a,11b-pentamethyl-5b,6,7,7a,8,11b,13,13a-octahydrooxireno[4,4a]isochromeno[6,5-g][2]benzoxepine-3,10,12(1H,5aH,10aH)-trione
- (5aR,7aS,8R,10aS,11aR,11bR)-8-(furan-3-yl)-12,12-dihydroxy-1,1,5a,7a,11b-pentamethyl-5a,5b,6,7,7a,8,11b,12,13,13a-decahydrooxireno[4,4a]isochromeno[6,5-g][2]benzoxepine-3,10(1H,10aH)-dione
- 14,15:21,23-Diepoxy-4,4,8-trimethyl-A,<span class="text-smallcaps">D</span>-dihomo-24-nor-4,17-dioxachola-1,20,22-triene-3,7,16-trione
- Ai3-37934
- Ccris 8657
- Obacunoic acid 3,4-lactone
- Obacunoic acid, eta-lactone
- Obacunoic acid, ε-lactone
- Obacunon
- Obakunone
- See more synonyms
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Found 10 products.
Obacunone
CAS:Obacunone is a naturally occurring limonoid, which is a type of triterpenoid compound. It is derived from the peels of citrus plants, particularly bitter and sweet oranges. Obacunone operates through several mechanisms, including inducing apoptosis, inhibiting cell proliferation, and modulating various signaling pathways. Its biological activity has garnered attention for its potential therapeutic benefits. In scientific research, Obacunone is primarily explored for its anticancer and anti-inflammatory properties. Studies have shown its efficacy in inhibiting the growth of certain cancer cell lines and reducing inflammation by affecting cytokine production. Additionally, it has antimicrobial and antioxidative potential, making it of interest in the development of new pharmaceuticals or nutraceuticals. With ongoing research, Obacunone's role in chemoprevention and therapy continues to expand, indicating its importance in future medical applications.Formula:C26H30O7Purity:Min. 95%Color and Shape:PowderMolecular weight:454.51 g/molObacunone
CAS:Obacunone: cytotoxic to prostate cells, anti-S. Typhimurium, may inhibit breast cancer and aromatase, trigger apoptosis.Formula:C26H30O7Purity:98% - ≥95%Color and Shape:White PowderMolecular weight:454.51Obacunone
CAS:LactoneFormula:C26H30O7Purity:≥ 95.0 % (HPLC)Color and Shape:PowderMolecular weight:454.52Obacunone
CAS:Obacunone is a novel activator of Nrf2, which exhibits anti-cancer, anti-inflammatory, antivirulence, insecticidal, anti-proliferative and anti-aromatase activities. Obacunone stimulates muscle hypertrophy and prevents obesity and hyperglycemia, and that these beneficial effects are likely to be mediated through the activation of TGR5 and inhibition of PPARγ transcriptional activity. Obacunone significantly inhibits aromatase activity in an in vitro enzyme assay with an IC50 value of 28.04 μM, and it also inhibits the p38 MAPK signaling pathway.Formula:C26H30O7Purity:95%~99%Molecular weight:454.519Obacunone
CAS:Formula:C26H30O7Purity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:454.52
