CAS: 75859-72-2

N-Desmethyl phenyltoloxamine hydrochloride is a white crystalline powder that is soluble in water and slightly soluble in ethanol. It has an analytical purity of greater than 99% with a melting point of 188-190°C. This compound is a metabolite of phenyltoloxamine, which is used as an analgesic and anti-inflammatory drug. N-Desmethyl phenyltoloxamine hydrochloride can be used as a pharmacopoeia reference standard for the analysis of this metabolite and also as a research and development starting material for the synthesis of other compounds.

Applications N-Desmethyl Phenyltoloxamine is a related compound to Phenyltoloxamine (P337370), a reagent in the enhancement of antitussive agents (antihistamines), in cold remedy formulations. Also shows mild antidepressant activity. References Kikumoto, R. et al.: J. Med. Chem., 24, 145 (1981); Berdy, G. et al.: J. Ocular Pharm., 7, 313 (1991); Meindl, W. et al.: Archiv. Pharm., 322, 493 (1989);