CAS 76-66-4: Rhynchophylline
Formula:C22H28N2O4
InChI:InChI=1S/C22H28N2O4/c1-4-14-12-24-10-9-22(17-7-5-6-8-18(17)23-21(22)26)19(24)11-15(14)16(13-27-2)20(25)28-3/h5-8,13-15,19H,4,9-12H2,1-3H3,(H,23,26)/b16-13+/t14-,15-,19-,22+/m0/s1
InChI key:InChIKey=DAXYUDFNWXHGBE-KAXDATADSA-N
SMILES:O=C1[C@@]2([C@]3(N(CC2)C[C@H](CC)[C@@H](\C(\C(OC)=O)=C/OC)C3)[H])C=4C(N1)=CC=CC4
Synonyms:- Corynoxan-16-carboxylic acid, 16,17-didehydro-17-methoxy-2-oxo-, methyl ester, (7β,16E,20α)-
- Mitrinermin
- Mitrinermine
- NSC 21731
- Rhyncholphylline
- Rhynchophyllin
- Rhyncophylline
- Spiro[3H-indole-3,1′(5′H)-indolizine]-7′-acetic acid, 6′-ethyl-1,2,2′,3′,6′,7′,8′,8′a-octahydro-α-(methoxymethylene)-2-oxo-, methyl ester, (αE,1′R,6′R,7′S,8′aS)-
- Spiro[3H-indole-3,1′(5′H)-indolizine]-7′-acetic acid, 6′-ethyl-1,2,2′,3′,6′,7′,8′,8′a-octahydro-α-(methoxymethylene)-2-oxo-, methyl ester, [1′R-[1′α,6′β,7′α(E),8′aβ]]-
- methyl (16Z)-16-(methoxymethylidene)-2-oxocorynoxan-17-oate
- methyl (3xi,16E,20alpha)-16-(methoxymethylidene)-2-oxocorynoxan-17-oate
- See more synonyms
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Found 11 products.
Rhynchophylline
CAS:Natural alkaloidFormula:C22H28N2O4Purity:≥ 90.0 % (HPLC)Color and Shape:PowderMolecular weight:384.48Rhynchophylline
CAS:Rhynchophylline is an indole alkaloid, which is naturally sourced from the Uncaria genus, specifically from Uncaria rhynchophylla. This alkaloid exhibits its mode of action primarily through non-competitive inhibition of NMDA receptors and L-type calcium channels. It has been observed to modulate both glutamatergic and serotonergic signaling pathways, which underscores its potential neurological impacts. The uses of Rhynchophylline are predominantly in the realm of neurological and cardiovascular research. In neuroscience, it is studied for its potential neuroprotective effects and its ability to attenuate excitotoxicity, which is of significant interest in the context of neurodegenerative diseases such as Alzheimer's and Parkinson's. Cardiovascularly, Rhynchophylline has been noted for its hypotensive effects, which are explored for therapeutic applications in hypertension. Furthermore, its anti-inflammatory and anti-arrhythmic properties continue to be focal points in preclinical studies. The comprehensive understanding of Rhynchophylline's mechanisms and effects is crucial for its potential incorporation into therapeutic strategies.Formula:C22H28N2O4Purity:Min. 95%Color and Shape:PowderMolecular weight:384.47 g/molRhynchophylline - Bio-X ™
CAS:This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formula:C22H28N2O4Purity:Min. 95%Color and Shape:PowderMolecular weight:384.47 g/molRhynchophylline
CAS:Formula:C22H28N2O4Purity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:384.48Rhynchophylline
CAS:Formula:C22H28N2O4Purity:≥ 98.0%Color and Shape:White to off-white powderMolecular weight:384.47Rhynchophylline
CAS:Rhynchophylline, a noncompetitive antagonist of the NMDA receptor, which has anti-inflammatory, anti-hypertension, cardiacprotective and neuroprotective activities. Rhynchophylline can markedly inhibit rabbit platelet aggregation induced by ADP or thrombin possibly by depressing the inflow of Ca2+ and the rise of the cytoplasmic free calcium level in platelet.Rhynchophylline can reduce the systolic blood pressure (SBP) of spontaneously hypertensive rats (SHR) significantly, decrease plasma Ang II, ADMA, and AT1R levels, and promote serum NO and NOS levels, which has the protection of vascular endothelial function.Formula:C22H28N2O4Purity:95%~99%Molecular weight:384.476Rhynchophylline
CAS:Rhynchophylline (Mitrinermine) is an alkaloid isolated from Crocus sativus and is widely used in anti-inflammatory and neuroprotective studies.Formula:C22H28N2O4Purity:99.44%Color and Shape:Red Brown Or White Fine PowderMolecular weight:384.47Rhynchophylline
CAS:Applications Rhynchophylline is a novel erythropoietin-producing hepatocellular A4 (EphA4) inhibitor. References Fu, A K.Y., et. al.: P. Natl. Acad. Sci. USA., 111, 9959 (2014)Formula:C22H28N2O4Color and Shape:NeatMolecular weight:384.47
