N-(6-chloro-5H-purin-2-yl)acetamide, with the CAS number 7602-01-9, is a purine derivative characterized by its structural features that include a purine ring system substituted with a chlorine atom and an acetamide group. This compound typically exhibits properties associated with purines, such as being a heterocyclic aromatic compound. It is often utilized in biochemical research and pharmaceutical applications due to its potential role as a nucleobase analog. The presence of the chlorine atom can influence its reactivity and biological activity, making it of interest in medicinal chemistry. The acetamide group contributes to its solubility and interaction with biological systems. In terms of stability, this compound is generally stable under standard laboratory conditions but may be sensitive to strong acids or bases. Its synthesis and characterization are important for understanding its role in various chemical and biological processes. Overall, N-(6-chloro-5H-purin-2-yl)acetamide serves as a valuable compound in the study of nucleic acids and related fields.

N-(6-chloro-5H-purin-2-yl)acetamide

7602-01-9: 2-(Acetylamino)-6-chloropurine

N-(6-Chloro-7H-purin-2-yl)acetamide

2-ACETAMIDO-6-CHLOROPURINE

2-Acetamido-6-chloropurine (2ACAP) is a nucleophilic agent that inhibits cancer cells by binding to the enzyme cholinesterase. It is used in the treatment of T-cell leukemia and herpes simplex virus. 2ACAP binds to the amine group of cholinesterase, which prevents it from breaking down acetylcholine. This inhibition leads to accumulation of acetylcholine, which has been shown to induce apoptosis in k562 cells. The molecular modeling study showed that 2ACAP binds to both chlorine atom and benzyl groups in the active site of cholinesterase. 2ACAP also has a potent inhibitory effect on cancer cell proliferation and can be used as an anti-cancer agent for many types of cancers including colon, breast, and prostate cancer.

CAS 7602-01-9: N-(6-chloro-5H-purin-2-yl)acetamide

N-(6-Chloro-7H-purin-2-yl)acetamide

Ref: 10-F234328

2-ACETAMIDO-6-CHLOROPURINE

Ref: IN-DA00G3IE

2-Acetamido-6-chloropurine

Ref: 3D-FA06027