![5-Chloro-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)s…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F383385-5-chloro-n2-2-methoxy-4-4-4-methyl-1-piperazinyl-1-piperidinyl-phenyl-n4-2-1-methylethyl-sulfonyl-phenyl-24-pyrimidinediamine.webp&w=3840&q=75)
CAS 761439-42-3: 5-Chloro-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-2,4-pyrimidinediamine
Formula:C30H40ClN7O3S
InChI:InChI=1S/C30H40ClN7O3S/c1-21(2)42(39,40)28-8-6-5-7-26(28)33-29-24(31)20-32-30(35-29)34-25-10-9-23(19-27(25)41-4)37-13-11-22(12-14-37)38-17-15-36(3)16-18-38/h5-10,19-22H,11-18H2,1-4H3,(H2,32,33,34,35)
InChI key:InChIKey=QQWUGDVOUVUTOY-UHFFFAOYSA-N
SMILES:N(C1=C(S(C(C)C)(=O)=O)C=CC=C1)C2=NC(NC3=C(OC)C=C(C=C3)N4CCC(CC4)N5CCN(C)CC5)=NC=C2Cl
Synonyms:- 2,4-Pyrimidinediamine, 5-chloro-N<sup>2</sup>-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N<sup>4</sup>-[2-[(1-methylethyl)sulfonyl]phenyl]-
- 5-Chloro-N<sup>2</sup>-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N<sup>4</sup>-[2-[(1-methylethyl)sulfonyl]phenyl]-2,4-pyrimidinediamine
- Ae 684
- Nvp-Tae 684
- Nvp-Tae684-Tae 684
- Nvt Tae-684
- Tae 684
- Tae684(Nvp-Tae684)
- 5-Chloro-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-2,4-pyrimidinediamine
- 2,4-Pyrimidinediamine, 5-chloro-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-
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Found 6 products.
NVP-TAE684
CAS:Inhibitor of NPM-ALK kinaseFormula:C30H40ClN7O3SPurity:Min. 95%Molecular weight:614.2 g/molNVP-TAE 684
CAS:NVP-TAE 684 (TAE684) is a excellently effective and specific ALK inhibitor(IC50=3 nM).Formula:C30H40ClN7O3SPurity:98% - 99.82%Color and Shape:SolidMolecular weight:614.2TAE684 (NVP-TAE684)
CAS:Formula:C30H40ClN7O3SPurity:98%Color and Shape:SolidMolecular weight:614.2017TAE 684
CAS:Controlled ProductApplications TAE 684 is a potent, selective, and efficacious inhibitor of NPM-ALK, a fusion protein that is a key regulator of oncogenic events that drives the survival and proliferation of anaplastic large-cell lymphomas. Potent ALK inhibitor References Schoenherr, C., et al.: Oncogene., 31, 5193 (2012); Tanizaki, J., et al.: Clin. Cancer. Res., 18, 6219 (2012); Heuckmann, J.M., et al.: Clin. Cancer. Res., 18, 4682 (2012);Formula:C30H40ClN7O3SColor and Shape:NeatMolecular weight:614.20
