CAS 762-04-9: Diethyl phosphite

Diethyl phosphite is precursor used for the synthesis of various organophosphorus compounds. used to prepare the nickel chloride-diethyl phosphite system, efficient catalyst for the cross-coupling reaction between various functionalized arylzinc halides and aryl bromides, triflates and activated chlorides. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Diethylphosphite, min. 95%

Diethyl phosphite used as intermediate for extraction agent and phosphoric acid esters. It is also used as solvent and acid acceptor in the synthesis of polypeptide. It is also used in the synthetic reaction. It is a precursor of phosphorous which is used for the synthesis of various organophosphorus compounds. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Diethyl phosphite is a chemical compound that is used as an intermediate in the synthesis of pharmaceuticals. It has been shown to be an effective inhibitor of prostate cancer cell growth, without exhibiting any cytotoxic effects on non-cancerous cells. This inhibition is attributed to the ability of Diethyl phosphite to form a complex with the hydroxyl group on DNA. The reaction mechanism of this compound involves the formation of a phosphate ester by reacting with trifluoroacetic acid and phosphorus pentoxide. The δ receptors are thought to be involved in this process, which may lead to future therapeutic treatments for prostate cancer that target these receptors and are more selective than Diethyl phosphite.

Applications Diethyl Phosphite, is an phosphorous precursor used for the synthesis of various organophosphorus compounds, acting as insecticide, and pesticides. References Kjoelholt, J., et al.: Chemosphere, 14, 1763 (1985); Zhou, Q., et al.: Atmospheric Environ., 43, 4163 (2009);