
CAS 76252-06-7: Nicainoprol
Formula:C21H27N3O3
InChI:InChI=1S/C21H27N3O3/c1-15(2)23-13-18(25)14-27-19-9-3-6-16-8-5-11-24(20(16)19)21(26)17-7-4-10-22-12-17/h3-4,6-7,9-10,12,15,18,23,25H,5,8,11,13-14H2,1-2H3
InChI key:InChIKey=AUIHHZBJBKRDIE-UHFFFAOYSA-N
SMILES:C(=O)(N1C2=C(OCC(CNC(C)C)O)C=CC=C2CCC1)C=3C=CC=NC3
Synonyms:- (+-)-1,2,3,4-Tetrahydro-8-(2-hydroxy-3-(isopropylamino)propoxy)-1-nicotinoylquinoline
- 1,2,3,4-Tetrahydro-8-(2-hydroxy-3-(isopropylamino)propoxy)-1-(3-pyridylcarbonyl)quinoline
- Methanone, [3,4-dihydro-8-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-1(2H)-quinolinyl]-3-pyridinyl-
- Nicainoprol [INN]
- Nicainoprolum
- Nicainoprolum [INN-Latin]
- Quinoline, 1,2,3,4-tetrahydro-8-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-1-(3-pyridinylcarbonyl)-
- Unii-1Ua960P80H
- [3,4-Dihydro-8-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-1(2H)-quinolinyl]-3-pyridinylmethanone
- {8-[2-hydroxy-3-(propan-2-ylamino)propoxy]-3,4-dihydroquinolin-1(2H)-yl}(pyridin-3-yl)methanone
- Nicainoprol
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Found 4 products.
Nicainoprol
CAS:Nicainoprol is a cardiac glycoside that is used as an anti-arrhythmic agent. It binds to the phospholipid membranes of cardiac muscle cells and inhibits the enzyme creatine kinase, which is necessary for the transfer of high-energy phosphate groups in the myocardium. This inhibition leads to a decrease in the rate at which ATP is synthesized. Nicainoprol has dose-dependent effects on cardiac function, with low doses causing an inhibitory effect and higher doses inducing proarrhythmia. The mechanism of nicainoprol’s action has been elucidated by kinetic data obtained from reconstituted preparations and from erythrocyte ghosts incubated with this drug. Nicainoprol also inhibits fatty acid oxidation in skeletal muscle cells, leading to increased levels of acetyl-CoA and citrate in these cells.Formula:C21H27N3O3Purity:Min. 95%Molecular weight:369.46 g/mol1,2,3,4-tetrahydro-8-[2-hydroxy-3-(isopropylamino)propoxy]-1-(3-pyridylcarbonyl)quinoline
CAS:Formula:C21H27N3O3Purity:99%Color and Shape:SolidMolecular weight:369.4574Nicainoprol
CAS:Nicainoprol (RU-42924) is a fast-sodium-channel blocking drug. Nicainoprol is a potent antiarrhythmic agent.Formula:C21H27N3O3Purity:99.54%Color and Shape:SolidMolecular weight:369.46Ref: TM-T4539
1mg140.00€5mg344.00€10mg512.00€25mg812.00€50mg1,093.00€100mg1,473.00€1mL*10mM (DMSO)350.00€