CAS 763-69-9: Ethyl 3-ethoxypropionate

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Ethyl 3-ethoxypropionate is used in the synthesis of phenols and selective inhibitors of cyclin-dependant kinase 4/6 for novel cancer therapies. It is also used as a solvent to prepare polymers. Further, it is used in paints and coatings. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Ethyl 3-ethoxypropionate is a cycloaddition product of ethyl 3-ethoxypropanoate. It has been shown to be more chemically stable than the reactants and has an increased uptake in the reaction solution. Ethyl 3-ethoxypropionate is able to undergo a cycloaddition process with diethyl succinate under conditions of high temperature and pressure, leading to the formation of methyl ethyl malonic acid. This chemical reaction takes place via an intermolecular hydrogen bonding interaction between the ethoxy group on one molecule and the ester group on the other molecule. The cyclohexane ring on each molecule also forms a hydrogen bonding interaction with its corresponding methyl or ethyl groups. Ethyl 3-ethoxypropionate is not reactive in its pure form but can undergo reactions when exposed to chemicals such as potassium hydroxide, which leads to its degradation into propionic acid and ethanol.

Ethyl 3-ethoxypropanoate

Ethyl 3-Ethyoxypropionate