CAS 766-85-8: 3-Iodoanisole

3-Iodoanisole

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications 3-Iodoanisole (cas# 766-85-8) is a compound useful in organic synthesis.

3-Iodoanisole is used to produce 3,3'-Dimethoxy-biphenyl. It can be used in agrochemical, pharmaceutical and dyestuff field. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

3-Iodoanisole is a reactive aryl halide that undergoes the Friedel-Crafts reaction with carbamic acid to produce anisole. The rate of this reaction is increased by the addition of nitrous acid, which is used as a catalyst. 3-Iodoanisole has two stereoisomers, one of which is more reactive than the other. This reactivity can be explained by electron-donating and electron-withdrawing effects on the substituents on the ring. The functional theory states that nucleophilic attack occurs at the carbon atom with least steric hindrance. 3-Iodoanisole reacts faster in hexane than in methanol because it has a lower boiling point and higher solubility in hexane.