CAS 76824-35-6: Famotidine
Formula:C8H15N7O2S3
InChI:InChI=1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)
InChI key:InChIKey=XUFQPHANEAPEMJ-UHFFFAOYSA-N
SMILES:N(C(=N)N)C1=NC(CSCCC(NS(N)(=O)=O)=N)=CS1
Synonyms:- 3-[(2-Diaminomethyleneaminothiazol-4-yl)methylthio]-N-sulfamoylpropionamidine
- 3-[([2-[(Diaminomethylidene)amino]-1,3-thiazol-4-yl]methyl)sulfanyl]-N-sulfamoylpropanimidamide
- 3-[({2-[(Hydrazonomethyl)amino]thiazol-4-yl}methyl)thio]-N-sulfamoylpropionamidine
- 3-[[2-(Diaminomethylideneamino)-1,3-thiazol-4-yl]methylsulfanyl]-N′-sulfamoylpropanimidamide
- 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfonyl)propanimidamide
- Agufam
- Amfamox
- Antodine
- Apo-Famotidine
- Apogastine
- Bestidine
- See more synonyms
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Famotidine for system suitability CRS
CAS:Famotidine for system suitability CRSFormula:C8H15N7O2S3Molecular weight:337.4454Famotidine
CAS:Famotidine is a selective histamine H2-receptor antagonist used in the treatment of gastric hypersecretory disorders. Famotidine is effective in the treatment of duodenal and gastric ulcers, particularly when they are caused by the prolonged use of nonsteroidal antiinflammatory drugs (NSAIDs). To improve retention in the stomach, famotidine has experimentally been formulated as buoyant tablets that remained floating for up to 10 hours in vitro (Jaimini, 2007).Formula:C8H15N7O2S3Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:337.45 g/molFamotidine
CAS:Formula:C8H15N7O2S3Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:337.44Famotidine
CAS:Compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structureFormula:C8H15N7O2S3Color and Shape:PowderMolecular weight:337.45Famotidine d4
CAS:Famotidine is a drug that belongs to the group of H2-receptor antagonists. It is a prodrug that is activated by hydrolysis in vivo and inhibits the gastric acid secretion by blocking the histamine-H2 receptor on parietal cells. Famotidine has been shown to reduce inflammation in squamous cell carcinoma and other tissues. It also reduces pain, swelling, and stiffness caused by rheumatoid arthritis or osteoarthritis. Famotidine binds to P-glycoprotein (Pgp) and prevents it from transporting drugs out of cells. This action inhibits the effect of nonsteroidal anti-inflammatory drugs, such as ibuprofen or naproxen, which are substrates for Pgp. Additionally, famotidine may inhibit the action of toll-like receptors which are implicated in inflammation.Formula:C8H11D4N7O2S3Purity:Min. 95%Molecular weight:341.47 g/mol3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]-N-sulfamoylpropanimidamide
CAS:Purity:98.0%Molecular weight:337.44000244140625Famotidine
CAS:Formula:C8H15N7O2S3Purity:≥ 98.0%Color and Shape:White to off-white powderMolecular weight:337.45Famotidine
CAS:Controlled ProductApplications Histamine H2-receptor antagonist. Antiulcerative. References Takeda, M., et al.: Arzneim.-Forsch., 32, 734 (1982), Miwa, M., et al.: J. Clin. Pharmacol. Ther. Toxicol., 22, 214 (1984), Takabatke, T., et al.: Eur. J. Clin. Pharmacol., 28, 327 (1985),Formula:C8H15N7O2S3Color and Shape:White To Off-WhiteMolecular weight:337.45Famotidine
CAS:Famotidine, a histamine H2-blocker, curbs gastric acid production, lowering volume and acidity.Formula:C8H15N7O2S3Purity:98.93% - 99.75%Color and Shape:White To Off-White Crystalline PowderMolecular weight:337.45
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