Thiamylal, with the CAS number 77-27-0, is a barbiturate derivative primarily used as an anesthetic agent. It is characterized by its rapid onset and short duration of action, making it suitable for induction of anesthesia. Thiamylal is a white crystalline powder that is soluble in water and exhibits a pH-dependent solubility profile. Its chemical structure includes a barbituric acid core, which contributes to its pharmacological properties. The substance acts as a central nervous system depressant, enhancing the effects of gamma-aminobutyric acid (GABA), a neurotransmitter that inhibits neuronal excitability. Due to its potency, thiamylal requires careful dosing and monitoring during use. It is important to note that, like other barbiturates, thiamylal has a potential for abuse and dependence, and its use has declined in favor of newer anesthetic agents with improved safety profiles. Proper handling and storage conditions are essential to maintain its stability and efficacy.

Thiamylal

77-27-0: 4,6(1H,5H)-Pyrimidinedione, dihydro-5-(1-methylbutyl)-5-(2-propen-1-yl)-2-thioxo-, 5-Allyl-5-(1'-methylbutyl)-2-thiobarbiturate, 5-Allyl-5-(1-Methylbutyl)-2-Thiobarbituric Acid, 5-Allyl-5-(1-methylbutyl)-2-thiobarbitursaure, Acide 5-Allyl-5-(1-Methylbutyl)-2-Thiobarbiturique, Acido 5-Alil-5-(1-Metilbutil)-2-Tiobarbiturico, Barbituric acid, 5-allyl-5-(1-methylbutyl)-2-thio-, Bio-Tal, Dihydro-5-(1-methylbutyl)-5-(2-propen-1-yl)-2-thioxo-4,6(1H,5H)-pyrimidinedione, Nsc 120815, Thiamylal, Thioseconal,  5-(1-methylbutyl)-5-prop-2-en-1-yl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione, 4,6(1H,5H)-Pyrimidinedione, dihydro-5-(1-methylbutyl)-5-(2-propenyl)-2-thioxo-

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CAS 77-27-0: Thiamylal

Thiamylal

Ref: TR-T344165

Thiamylal

Ref: 3D-AAA07727

Thiamylal RS

Ref: 2K-1079000021