CAS: 773059-19-1

Rucaparib hydrochloride (AG014699) is an oral PARP inhibitor with Ki 1.4 nM for PARP1 and hinders H6PD, studied in CRPC research.

8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-azepino[5,4,3-cd]indol-6-one monohydrochloride is a polymerase activating agent that activates the polymerase and promotes the synthesis of DNA. It is used in industrial processes to synthesize polyadpribose. 8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-azepino[5,4,3-cd]indol-6-one monohydrochloride also has antiangiogenic properties and can inhibit the growth of cancer cells. 8FMAZ is synthesized from dioxolane and fluorine in an acidic solution with an inorganic base. The reaction time for