CAS: 77603-42-0

GNF-PF-3777 (8-Nitrotryptanthrin) (8-Nitrotryptanthrin) is a potent inhibitor of human indoleamine 2,3-dioxygenase 2 (hIDO2; Ki: 0.97 μM).

GNF-PF-3777 is a potent immunostimulatory agent that has been shown to inhibit tumor growth and cancer. It is an anticarcinogenic compound that inhibits the metabolism of tryptophan by blocking the enzyme tryptophan 2,3-dioxygenase (TDO). GNF-PF-3777 has also been shown to increase the effectiveness of antigen-based immunotherapy. This drug has potent anti-inflammatory and antiviral properties, which are mediated by the inhibition of NFκB.

GNF-PF-3777

8-Nitrotryptanthrin