Phosphine oxide, di-2-naphthalenyl- is an organophosphorus compound characterized by the presence of a phosphorus atom bonded to two naphthyl groups and an oxygen atom, forming a phosphine oxide functional group. This compound typically exhibits a white to light yellow solid appearance and is known for its stability under ambient conditions. It is soluble in organic solvents, which makes it useful in various chemical applications, including as a ligand in coordination chemistry and as a reagent in organic synthesis. The presence of the naphthyl groups contributes to its aromatic character, potentially influencing its reactivity and interaction with other chemical species. Additionally, phosphine oxides are generally recognized for their ability to act as electron donors, which can enhance their utility in catalysis and material science. Safety data indicates that, like many organophosphorus compounds, it should be handled with care due to potential toxicity and environmental concerns. Proper safety protocols should be followed when working with this substance in laboratory settings.

Phosphine oxide, di-2-naphthalenyl-

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Di(naphthalen-2-yl)phosphine oxide

Di(naphthalen-2-yl)phosphine oxide (DNPO) is a reagent used in organic chemistry for the oxidative and dehydrative coupling of amines, alcohols, and other functional groups. DNPO is also used as an additive to improve yields in cross-coupling reactions. This compound can be prepared by reacting 2-naphthol with phosphorus pentoxide followed by oxidation of the resulting diol with nitric acid. The method is catalyzed by organocatalysis using copper salts or organocopper compounds. DNPO has been shown to be an efficient catalyst for biomolecular synthesis such as benzothiazoles, dialkyl phosphates, and methylphosphonates.

CAS 78871-05-3: Phosphine oxide, di-2-naphthalenyl-

Di(naphthalen-2-yl)phosphine oxide

Ref: IN-DA008NLA

Di(naphthalen-2-yl)phosphine oxide

Ref: 10-F499161

Di(naphthalen-2-yl)phosphine oxide

Ref: 3D-DDA87105

Bis(2-naphthyl)phosphine oxide

Ref: 54-OR79516