CAS 79-08-3: Bromoacetic acid

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Bromoacetic acid

Bromoacetic acid is used in organic synthesis and as an alkylating agent. It is also used as a biochemical for proteomics research. It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, dyes and agrochemicals. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Bromoacetic acid is a brominated carboxylic acid that has been shown to bind to response elements and inhibit the synthesis of proteins. It has been shown to inhibit the growth of bacteria in human serum at concentrations of 1-5 mM. Bromoacetic acid also binds to metals, such as copper and zinc, and inhibits their activity. This compound has also been shown to have anti-inflammatory properties in experimental models. Bromoacetic acid is not toxic in rats, but it may cause myocardial infarction in humans.

Applications Bromoacetic Acid is a relatively strong alkylating agent as well as a versatile building block used very commonly in organic synthesis. Bromoacetic acid has been shown to reversibly inhibit human erythrocyte carbonic anhydrase B. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Song, C. et al.: J. Org. Synth., 74, 8980 (2009); Kramer, S.P. et al.: J. Nat. Cancer Inst., 31, 297 (1963); Whitney, P.L. et al.: Eur. J. Biochem., 16, 126 (1970);

BR1015 - Bromoacetic acid