CAS 80-08-0: Dapsone
Formula:C12H12N2O2S
InChI:InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2
InChI key:InChIKey=MQJKPEGWNLWLTK-UHFFFAOYSA-N
SMILES:S(=O)(=O)(C1=CC=C(N)C=C1)C2=CC=C(N)C=C2
Synonyms:- 1,1'-Sulfonylbis[4-aminobenzene]
- 1358F
- 4,4'-Dapsone
- 4,4'-Dds
- 4,4'-Diamino Diphenyl Sulfone
- 4,4'-Diamino Diphenyl Sulphone
- 4,4'-Diaminodiphenylsulfon
- 4,4'-Diaminodiphenylsulfone
- 4,4'-Sulfonylbisaniline
- 4,4'-Sulfonylbisbenzamine
- 4,4'-Sulfonyldiphenylamine
- See more synonyms
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Dapsone
CAS:Other aromatic organo-sulfur compounds (excluding pesticides)Formula:C12H12N2O2SColor and Shape:White Off-White Light Yellow Crystalline PowderMolecular weight:248.06195Dapsone
CAS:Controlled ProductApplications An antibacterial used in the treatment of dermatitis herpetiformis. References Francis, J., et al.: Br. J. Pharmacol., 5, 565 (1950), Uetrecht, J., et al.: Clin. Dermatol., 7, 111 (1989); Reszka, K., et al.: Chem. Res. Toxicol., 22, 1137 (2009), Santos, J., et al.: Bioorg. Med. Chem., 17, 3795 (2009), Varma, M., et al.: J. Med. Chem., 52, 4844 (2009),Formula:C12H12N2O2SColor and Shape:NeatMolecular weight:248.30Di-(4-(4'-Aminidiphenylsulphone))amine
CAS:Controlled ProductFormula:C24H21N3O4S2Color and Shape:NeatMolecular weight:479.571Dapsone
CAS:Dapsone is a nonsteroidal anti-inflammatory drug that is used to treat various types of infectious diseases and skin disorders. It acts by blocking the synthesis of dihydrofolic acid, which leads to inhibition of bacterial growth. Dapsone inhibits the activity of monoethyl ether reductase (NADH) in human polymorphonuclear leukocytes, which slows the production of hydrogen peroxide and prevents oxidative damage to cellular components. It has been shown to be effective against both erythema multiforme and chronic dermatitis herpetiformis with minimal side effects. The use of dapsone may be helpful in diagnosis as it can inhibit polymerase chain reactions that are specific for squamous cells. There are also reports that dapsone may affect intestinal motility and cause bowel disease.Formula:C12H12N2O2SPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:248.3 g/mol4,4'-Diaminodiphenyl sulfone, 98%
CAS:It is active against a wide range of bacteria, but is mainly employed for its actions against Mycobacterium leprae, being used as part of multidrug regimens in the treatment of all forms of leprosy. It is a second-line medication for the treatment and prevention of Pneumocystis pneumonia and for the prevention of toxoplasmosis in those who have poor immune function. Additionally, it has been used for acne as well as other skin conditions. Moreover it is employed as an anti-inflammatory drug, anti-infective drug, a leprostatic drug and an antimalarial drug. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C12H12N2O2SPurity:98%Color and Shape:White to pale cream, PowderMolecular weight:248.30Dapsone
CAS:Formula:C12H12N2O2SPurity:(Titration) 98.0 - 102.0 %Color and Shape:White to off-white crystalline powderMolecular weight:248.304-Aminophenyl sulfone, 97%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C12H12N2O2SPurity:97%Color and Shape:Crystalline powder, White to beigeMolecular weight:248.304-[(4-aminobenzene)sulfonyl]aniline
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:248.30000305175784,4'-Sulfonyldianiline
CAS:Formula:C12H12N2O2SPurity:98%Color and Shape:SolidMolecular weight:248.30088Dapsone
CAS:Dapsone (Sulphadione) has activity against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae.Formula:C12H12N2O2SPurity:99.84%Color and Shape:White To Creamy Solid CrystallineMolecular weight:248.3Bis(4-aminophenyl) Sulfone
CAS:Bis(4-aminophenyl) SulfoneFormula:C12H12N2O2SPurity:97%Color and Shape: off-white solidMolecular weight:248.30g/mol
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