CAS 8003-34-7: Pyrethrins

Pyrethrum is a natural insecticide that is extracted from the flowers of the chrysanthemum plant. This extract contains pyrethrins, which are a type of pyrethroids. Pyrethrins disrupt the function of insect nerve cells and muscle contractions. The matrix effect refers to the increased potency of pyrethrum when it is combined with other compounds such as lindane or permethrin. Colloidal gold has been used as a model system to study how these compounds work in insects. Treatment trials have shown that pyrethrum can be effective in combating insects like cockroaches, flies, and mosquitoes. Pyrethrum also has anti-inflammatory properties and may be used for treatment of skin conditions such as eczema and psoriasis. Chromatographic analysis has shown that pyrethrin (the active component) consists of a signal peptide, which is cleaved in vivo to release the active compound, followed by an inactive peptide called piper

Pyrethrins, a mixture of insecticidal compounds derived from the Chrysanthemum flower, demonstrate efficacy against C. fatigans mosquitoes at a concentration of 200 mg/ft^2, either alone or when combined with piperonyl butoxide on glass, wood, or mud panels, maintaining effectiveness for 3-4 weeks. This compound exhibits toxicity through oral administration and inhalation in rats (LC50s = 700 and 1,030 mg/kg for females and males, respectively; LD50= 3.4 mg/L) and to rainbow trout (LC50= 52.2 µg/L), highlighting its broad-spectrum insecticidal capabilities. Pyrethrins are utilized in agricultural and horticultural insect control formulations. Designed solely for research and analytical applications, this product is restricted to controlled laboratory environments and is not available in bulk sizes.

Stability Light Sensitive Applications Pyrethrum Extract is used as a component in pesticides and insecticides. Pyrethrum Extract is a sum of a mixture of six various pyrethrine compounds, which are derived from Chrysanthemum cinerariifolium plants.Useful in cannabis testing kits as a component of pesticide mixes (P698230). Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Keiding, J. et al.: Pesticide Sci., 7, 283 (1976)

Pyrethrum is a natural insecticide that belongs to the group of pyrethroids. It is a mixture of four related compounds, including three esters (pyrethrin) and one ether (pyrethroid). Pyrethrum has been shown to be genotoxic in mammalian cells and to cause neuronal death in mice. It has also been found to have insecticidal properties against mosquitoes, flies, fleas, and ticks. The matrix effect of pyrethrum on insects may be due to its ability to inhibit voltage-gated sodium channels.