CAS 8015-61-0: Aloin

Aloin

Aloin(mixture of A&B)

Aloin is a natural anthraquinone glycoside, which is derived from the latex of Aloe species, particularly Aloe vera and Aloe ferox. This compound is primarily located beneath the plant's outer leaf skin. Aloin acts by stimulating peristalsis in the large intestine, thereby facilitating bowel movements. This action is primarily due to the conversion of aloin to aloe-emodin-9-anthrone by intestinal bacteria, which then irritates the bowel. Aloin's primary application is as a laxative, often utilized in the treatment of constipation. Its action is typically observed within 6-12 hours of ingestion, making it an effective short-term solution for bowel regulation. However, due to its potency, aloin's use is generally recommended to be limited to short durations to avoid potential side effects such as cramping or dependency. Its application has also been explored in scientific studies related to its possible antioxidative and anti-inflammatory properties, though these uses are secondary to its primary function as a laxative. Given the potential variability in response, aloin's use is often carefully controlled in pharmaceutical contexts.

ALOIN Inhibits Interleukin (IL)-1β-Stimulated IL-8 Production in KB Cells.