CAS 80952-72-3: (5xi,6beta,9xi,12alpha,13xi,14beta,17alpha,20R)-3,12,20-trihydroxydammar-24-en-6-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside

20(R)Ginsenoside Rg2 is a bioactive compound, specifically a saponin, derived from Panax ginseng, a perennial plant in the Araliaceae family. This compound is one of the ginsenosides, which are the primary active constituents responsible for ginseng's pharmacological properties. Its mode of action involves modulation of cellular signaling pathways and neurotransmitter regulation, which contributes to its neuroprotective and cognitive enhancing effects. In scientific studies, 20(R)Ginsenoside Rg2 has shown promise in various applications, particularly in neuroprotection against oxidative stress and in the improvement of cognitive functions. It is being investigated for its potential to inhibit apoptosis in neural cells, enhance synaptic plasticity, and reduce neuroinflammation, which could have implications in the treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's. Furthermore, its capacity to modulate ion channels and receptors presents a broad area for research, specifically in the context of neurological health and therapeutic development. Continued investigations are necessary to fully understand its efficacy and potential applications in clinical settings.

Applications 20(R)-Ginsenoside Rg2 possesses potent bioactivities and abundance in natural sources such as the roots, rhizomes and stem-leaves of Panaz ginseng. Also, it exhibits stereoselective inhibitory effects of varying degrees on the ten UGT isoenzymes. References Ma, L., et al.: Molecules, 21, 757/1-757/15 (2016); Kim, D., et al.: Tox. Lett., 259, 1-10 (2016)

20(R)-Ginsenoside Rg2 (20R-Ginsenoside Rg2) is a compound with anti-oxidant and anti-apoptosis.

20(R)-Ginsenoside Rg2