CAS 82499-03-4: 2-Amino-6-bromopurine
Formula:C5H4BrN5
InChI:InChI=1S/C5H4BrN5/c6-3-2-4(9-1-8-2)11-5(7)10-3/h1H,(H3,7,8,9,10,11)
InChI key:InChIKey=HPGBGNVPUMCKPM-UHFFFAOYSA-N
SMILES:BrC1=C2C(=NC(N)=N1)N=CN2
Synonyms:- (6-Bromo-9H-purin-2-yl)amine
- 1H-Purin-2-amine, 6-bromo-
- 6-Bromo-9H-purin-2-amine
- 6-bromo-5H-purin-2-amine
- 6-bromo-7H-purin-2-amine
- 9H-Purin-2-amine, 6-bromo-
- NSC 67618
- Purine, 2-amino-6-bromo-
- d2-Amino-6-bromopurine
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Found 4 products.
6-Bromo-7H-purin-2-amine
CAS:Formula:C5H4BrN5Purity:98%Color and Shape:SolidMolecular weight:214.02282-Amino-6-bromopurine, 98%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C5H4BrN5Purity:98%Color and Shape:Yellow to orange, PowderMolecular weight:214.032-Amino-6-bromopurine
CAS:2-Amino-6-bromopurine is a cancer drug that is currently undergoing clinical trials for the treatment of prostate cancer. This drug has shown to be effective in treating prostate cancer cells that are resistant to castration, which are not sensitive to this hormone. 2-Amino-6-bromopurine inhibits DNA polymerase, leading to apoptosis in prostate cancer cells. It also interacts with the thiopurine S-methyltransferase enzyme, which leads to the production of 6-mercaptopurine and 6-thioguanine, which can block DNA synthesis by inhibiting ribonucleotide reductase and thymidylate synthase. 2-Amino-6-bromopurine has been shown to inhibit mutations associated with metastatic castration resistant prostate cancer.Formula:C5H4BrN5Purity:Min. 95%Molecular weight:214.02 g/mol
