![2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorop…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F375406-2-pyridinecarboxamide-4-4-4-chloro-3-trifluoromethyl-phenyl-amino-carbonyl-amino-3-fluorophenoxy-1-oxide.webp&w=3840&q=75)
CAS 835621-12-0: 2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-, 1-oxide
Formula:C20H13ClF4N4O4
InChI:InChI=1S/C20H13ClF4N4O4/c21-14-3-1-10(7-13(14)20(23,24)25)27-19(31)28-16-4-2-11(8-15(16)22)33-12-5-6-29(32)17(9-12)18(26)30/h1-9H,(H2,26,30)(H2,27,28,31)
InChI key:InChIKey=JPEWXTSDCNCZOD-UHFFFAOYSA-N
SMILES:O(C=1C=C(C(N)=O)N(=O)=CC1)C2=CC(F)=C(NC(NC3=CC(C(F)(F)F)=C(Cl)C=C3)=O)C=C2
Synonyms:- 2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-, 1-oxide
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Found 9 products.
N-Desmethyl Regorafenib (Pyridine)-N-oxide-d3
CAS:Controlled ProductApplications N-Desmethyl Regorafenib (Pyridine)-N-oxide-d3 is the isotope labelled analog of N-Desmethyl Regorafenib (Pyridine)-N-oxide (D293280); a synthetic metabolite of Regorafenib (R143000) used for treatment and prevention of cancer. References Wilhelm, S.: PCT Int. Appl. WO 2011130728 A1 20111020. Oct 20, 2011Formula:C20D3H10ClF4N4O4Color and Shape:NeatMolecular weight:487.807N-Desmethyl Regorafenib-d3 N-Oxide
CAS:Formula:C20H10D3ClF4N4O4Color and Shape:Yellow SolidMolecular weight:487.81N-Desmethyl Regorafenib N-Oxide (M5 Metabolite)
CAS:Formula:C20H13ClF4N4O4Color and Shape:White To Off-White SolidMolecular weight:484.80N-desmethyl Regorafenib N-oxide
CAS:N-Desmethyl Regorafenib N-oxide, an active metabolite of the multi-kinase inhibitor regorafenib, originates through the action of the cytochrome P450 (CYP) isoform CYP3A4. This compound demonstrates efficacy in vitro by inhibiting key enzymes such as VEGFR2, Tie2, c-Kit, and B-RAF, and it exhibits tumor growth inhibition in HT-29 and MDA-MB-231 mouse xenograft models at a dosage of 1 mg/kg.Formula:C20H13ClF4N4O4Color and Shape:SolidMolecular weight:484.79Regorafenib metabolite M5
CAS:Regorafenib metabolite M5 is a drug product that is custom synthesized by our company and has high purity. It can be used in metabolism studies, drug development, and pharmacopoeia due to its natural origin. It is also a synthetic compound that can be used as an impurity standard or research and development standard in HPLC.Formula:C20H13ClF4N4O4Purity:Min. 95%Molecular weight:484.79 g/molN-Desmethyl Regorafenib (Pyridine)-N-oxide
CAS:Controlled ProductStability Light Sensitive Applications N-Desmethyl Regorafenib (Pyridine)-N-oxide is a synthetic metabolite of Regorafenib (R143000) and is used for treatment and prevention of cancer. References Wilhelm, S.: PCT Int. Appl. WO 2011130728 A1 20111020. Oct 20, 2011Formula:C20H13ClF4N4O4Color and Shape:NeatMolecular weight:484.79
